The Center for Clinical Epidemiology and Biostatistics (CCEB) was created in 1993 to provide an interdepartmental structure linking clinical epidemiologists and biostatisticians within the University of Pennsylvania Health System (UPHS). Through its predecessor, the Clinical Epidemiology Unit, the CCEB has been actively involved in clinically-oriented epidemiological and biostatistical teaching and research since 1978.

The Department of Biostatistics and Epidemiology (DBE) was created in 1994. Its primary objectives are to provide: 1) an academic home for biostatisticians and non-clinician epidemiologists and 2) an academic structure to support primary research in biostatistics and epidemiology.

Together, the CCEB and DBE provide consultation on issues of study design and statistical analysis within UPHS; facilitate collaborative research involving clinicians, biostatisticians, and non-clinician epidemiologists; and provide training in biostatistics and epidemiology. Now consisting of more than 500 individuals, the CCEB and DBE are the primary home for epidemiology and biostatistics at the University of Pennsylvania.

Center and Department Structure and Key Personnel

Center/Department and Unit/Division organization and leadership.


A history of clinical epidemiology and biostatistics efforts at Penn.

CCEB Mission Statement

The CCEB's mission, objectives, and strategies for achieving its objectives.

DBE Mission Statement

The DBE's mission, objectives, and strategies for achieving its objectives.


The CCEB and DBE manage multiple teaching programs designed for medical students, residents, fellows, graduate students, and faculty.


The CCEB and DBE have a large, diverse, and active research program.

Study Design and Biostatistics Services

The CCEB and DBE offer biostatistical support for collaborative research projects, as well as study design and biostatistical consultation on matters related to proposal development.

Project and Data Management Services

The CCEB and DBE provide support for the development and implementation of large-scale, multicenter clinical trials, collaborative clinical and patient-oriented research, and multi-institutional health services research projects.

Professional Development

The CCEB and DBE support FOCUS on Health & Leadership for Women, a program designed to support the advancement and leadership of women in academic medicine and to promote education and research in women's health.

Community Impact

CCEB and DBE faculty lead several community health programs and projects.

Resources and Environment

CCEB and DBE office space, laboratory space, and computing resources.

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