Clinical Epidemiology Courses

To view the times of the courses listed below, please refer to the corresponding term schedule:
Fall term schedule
Spring term schedule
Summer term schedule

If you are outside the Center for Clinical Epidemiology and Biostatistics (CCEB) and would like to take a class, please note you will need to obtain faculty permission as well as speak with Jenn Kuklinski to ensure space is available. The Epidemiology program does not allow auditing of any type.

Please contact The Office of Graduate Training in Epidemiology if you have any questions about the course timetable or any of the courses offered below.

 

EPID 510 - Introductory Epidemiology
Summer II Term
1 course unit
Prerequisite: Permission of instructor

Instructor: James Lewis, MD, MSCE
This course is a series of lectures and workshops, designed to teach basic principles of epidemiologic research design. The course provides an overview of the types of research questions that can be addressed by epidemiologic methods. Topics covered include: definitions of epidemiology; measures of disease frequency; measures of effect and association; epidemiologic study designs, both experimental and non-experimental; and an overview of analysis of epidemiologic studies.

 

EPID 516 - Disease Ecology
Spring Term (Please check with Department as this course is not offered every year)
1 course unit
Prerequisite: Permission of instructor

Instructor: Michael Levy, PhD
The transmission of infectious diseases is a complex and ever-changing process, and the measures we have to protect ourselves against pathogens-vaccines, antibiotics, bed nets-can have equally complex and unpredictable outcomes. The aim of disease ecology is to understand pathogens and their hosts as interacting populations and to use such understanding to design rational strategies to curb or eliminate disease transmission.

 

EPID 518 (PUBH 517) – Geography & Public Health
1 course unit
Prerequisite: Permission of instructor

Instructor: Charles Branas, PhD and Douglas J. Wiebe, PhD
This course will provide an introduction to GIS in public health research and practice.  Through a series of lectures and labs students will explore theories linking health and the environment, spatial analysis and spatial epidemiology, and applications of GIS-related data collection and analysis.

 

EPID 526 - Biostatistics for Epidemiologic Methods I
Summer II/Fall Term
1 course unit
Prerequisite: Permission of instructor

Instructors: Matthew Bryan, PhD and Andrew Cucchiara, PhD
Lab Instructor: Vincent Lo Re, MD, MSCE and Kimberly Forde, MD, MHS
The first half of this will cover graphical methods, probability, discrete and continuous distributions, estimation, confidence intervals, and one sample hypothesis testing. Emphasis is placed on understanding the proper application and interpretation of the methods. The second half of this course will cover two sample hypothesis testing, nonparametric techniques, sample size determination, correlation, regression, analysis of variance, and analysis of covariance. Emphasis is placed on understanding the proper application and underlying assumptions of the methods presented. Laboratory sessions focus on the use of the STATA statistical package and applications to clinical data.

 

EPID 527 - Biostatistics for Epidemiologic Methods II
Fall/Spring Term
1 course unit
Prerequisite: Permission of instructor

Instructors: J. Richard Landis, PhD and Pamela A. Shaw, PhD, MS
Lab Instructor: Vincent Lo Re, MD, MSCE and Kimberly Forde, MD, MHS
The first half of this covers concepts in biostatistics as applied to epidemiology, primarily categorical data analysis, analysis of case-control, cross-sectional, cohort studies, and clinical trials. Topics include simple analysis of epidemiologic measures of effect; stratified analysis; confounding; interaction, the use of matching, and sample size determination. Emphasis is placed on understanding the proper application and underlying assumptions of the methods presented. Laboratory sessions focus on the use of the STATA and other statistical packages and applications to clinical data. The second half of this course covers concepts in biostatistics as applied to epidemiology, primarily multivariable models in epidemiology for analyzing case-control, cross-sectional, cohort studies, and clinical trials. Topics include logistic, conditional logistics, and Poisson regression methods; simple survival analyses including Cox regression. Emphasis is placed on understanding the proper application and underlying assumptions of the methods presented. Laboratory sessions focus on the use of the STATA and other statistical packages and applications to clinical data.

 

EPID 532 - Database Management for Clinical Epidemiology
Spring term
0.5 course units
Prerequisite: Permission of instructor

Instructor: John Holmes, PhD
This course provides students with an introduction to the techniques of database management as they apply to clinical research. Students learn how to design and implement computerized databases, perform basic query and reporting operations, migrate data between various file formats, prepare databases for statistical analysis, and perform quality assurance procedures. This course focuses on the practical issues of database management and is intended to support each student’s planned research enterprise. Each class session will be preceded by a one-hour online lecture and brief self-assessment quiz to be completed prior to attending class. This lecture is intended to prepare students for the class for that week, which will be dedicated to practical experience in a laboratory setting.

 

EPID 540 - Injury and the Public's Health
Spring term (Please check with Department as this course is not offered every year)
1 course unit
Prerequisite: Permission of instructor

Instructor: Charles Branas, PhD
This course offers students an introduction to the field of injury and violence prevention. As a major cause of death and disability throughout the world, injury is a leading public health problem. Prominent types of injuries to be discussed include those relating to motor vehicles, falls, and firearms. Behavioral, biological, economic, and social issues concerning the implementation of injury reduction policies are emphasized through case studies as well as injuries in the workplace, in the home, and during recreation.

 

EPID 542 - Measurement of Health in Epidemiology
Fall term
1 course unit
Prerequisite: Permission of instructor

Instructor: Douglas J. Wiebe, PhD
Epidemiologic analyses involve three types of procedures: measuring variables, estimating population parameters, and testing statistical hypotheses.  This course addresses the first of these procedures: measurement, which broadly encompasses the tasks involved in obtaining data, without which analyses cannot proceed.  Course topics to be discussed: defining the concepts of exposure, disease, and health; approaches to measuring exposures, which may be personal (psychological behavioral, biological, or genetic) or environmental (physical, chemical, social, or organizational); approaches to measuring disease and health status; assessing the validity and reliability of measurement instruments; problems of misclassification of exposure status and disease status and problems of missing data; instrument development; and qualitative methods.

 

EPID 550 - Clinical Economics and Clinical Decision Making
Spring term
1 course unit
Prerequisite: Permission of instructor

Instructors: Sankey Williams, MD and Henry Glick, PhD
This course focuses on the application of decision analysis and economic analysis to clinical and policy research. The course begins with material about the selection, use, and analysis of diagnostic tests using two by two tables, likelihood ratios, and ROC curves. The course continues with the introduction of more general tools for decision analysis, including decision trees and other mathematical models. Special emphasis is placed on the assessment and use of utilities in these models. A major focus of the course is the application of economic principles to the evaluation of health outcomes. During seminars, students will carry out practical exercises that include problem solving, critically analyzing published articles, and learning to use computer software that facilitates decision and economic analyses.

 

EPID 560 - Issues in Research Protocol Development
Spring term
0.25 course unit
Prerequisite: Candidates for the Masters in Clinical Epidemiology degree only

Instructors:Kurt Barnhart, MD, MSCE, Amanda Anderson, PhD, MPH, Jun Mao, MD, MSCE, and Peter Reese, MD, MSCE
This is a seminar that focuses on major issues in research protocol development, including methodological issues regarding different research designs, development of research questions, and plans for analysis. Each student will present his or her research proposal for open discussion during one of the seminar sessions.

 

EPID 570 - Critical Appraisal of the Medical Literature
Spring term
0.25 course units
Prerequisite: Candidates for the Masters in Clinical Epidemiology degree only
Instructors:
Meenakshi Bewtra, MD, MPH, Sandra Amaral MD, MHS, and Elizabeth Lowenthal, MD, MSCE
This seminar focuses on techniques for critical appraisal of the medical literature. Each student will be responsible for at least one critical appraisal session covering different epidemiologic topics (including the evaluation of diagnostic tests, clinical course and prognosis of disease, disease etiology or causation, therapy, quality of clinical care, economic evaluation, and meta-analysis). For his/her session, each student will appraise critically a journal article and lead the discussion concerning that article.

 

EPID 575 - Introduction to Genetic Epidemiology
Spring term
1 course unit
Prerequisite: Permission of instructor

Instructors: Timothy Rebbeck, PhD and Marcella Devoto, PhD
Recent advances have made it feasible to incorporate data on potential genetic risk factors into traditional epidemiologic studies. Hence, there is an increasing need for epidemiologists to understand the genetic basis of disease, read, and interpret genetic studies, and incorporate the collection and analysis of genetic information into studies of disease etiology. The objectives of this course are to provide epidemiologists with an understanding of: 1) basic genetics, 2) the tools used by geneticists and genetic epidemiologists, and 3) the integration of genetic data into traditional epidemiologic study designs. After completing this course, students will be able to read and interpret genetic epidemiologic studies. In addition, they will be able to design epidemiologic studies that incorporate genetic data collection and analysis.

 

EPID 580 - Outcomes Research
Fall term
1 course unit
Prerequisite: EPID 526 or equivalent, EPID 527 or equivalent, and permission of instructor

Instructor: Jeffrey Silber, MD
This course is divided into two main parts. The first part addresses issues related to the measurement of quality in health care. Included is a review of the classical structure-process-outcome quality paradigm. The paradigm's strengths and limitations are addressed. This part especially focuses on outcome measures of quality, and examine the validity of alternative measures. The second part deals with observational, or quasi-experimental, research studies. It addresses the advantages and limitations of alternative designs, and covers the role of clinical risk adjustment in observational studies of medical interventions. It focuses on the problem of selection bias, and reviews recent methods for dealing with this bias, such as instrumental variables.

 

EPID 582– Systematic Reviews & Meta-Analysis
Fall term (Please check with Department as this course is not offered every year)
1 course unit
Prerequisite: EPID 510 or equivalent & EPID 526 or equivalent (may be taken concurrently) and permission of instructor
Instructor: James Guevara, MD, MPH and Craig Umscheid MD, MSCE
This course will provide an introduction to the fundamentals of systematic reviews and meta-analysis.  It will cover introductory principles of meta-analysis; protocol development; search strategies; data abstraction methods; quality assessment; meta-analytic methods; and applications of meta-analysis.  The course is composed of a series of weekly small group lectures and discussion, including critical appraisal of published papers and protocol presentations.

 

EPID 610 - Tutorial in Epidemiologic Research
Fall, Spring and Summer terms
1 course unit
Prerequisite: Candidates for the Masters in Clinical Epidemiology degree only

Instructor: CCEB faculty
This is a tutorial given by each student's advisor. Advisor and student meet regularly, usually weekly. Topics include: discussion and review of epidemiologic concepts and principles, guided readings in the epidemiology of a specific health area, and the development of the research protocol. Credit for this course is awarded upon completion of a research project proposal, the one to be used to fulfill the MSCE thesis requirement, which must be approved by the student's advisor. Evaluation is based on the grade received for the proposal.

 

EPID 621 - Longitudinal and Clustered Data
Fall Term
1 course unit
Lecture and labs
Prerequisite: Completion of EPID 527 or equivalent preparation in biostatistics, including generalized linear models, principles of first-year calculus and matrix algebra. Permission of instructor
Instructor: A. Russell Localio, PhD
An introduction to the principles of and methods for longitudinal and clustered data analysis with special emphasis on clinical, epidemiologic, and public health applications; marginal and conditional methods for continuous and binary outcomes; mixed effects and hierarchical models; and simulations for power calculations. Each student will be required to participate in 8 labs and complete associated problem sets. Knowledge of Stata and SAS.

 

EPID 622 Applied Regression Models for Categorical Data
Fall Term (first half of term)
0.5 course unit
Prerequisite: EPID 510 or equivalent and EPID 526 or equivalent

Instructor: Justine Shults, PhD
This course will provide in-depth treatment of several topics in categorical data analysis. After a brief review of methods for contingency tables, we will introduce the idea of generalized linear models, and focus on two special cases – multiple logistic regression and loglinear models. Each topic will be presented in detail by stating the model and covering parameter estimation and interpretation, inference, model building, regression diagnostics and assessment of model fit. Finally, we will cover extensions to both models, including models for multinomial data, analysis of matched-pair data, and random effects models. Topics will be illustrated in class with examples, and we will discuss the use of Stata to conduct the analyses.

 

EPID 623 Survival Data Analysis
Fall Term (second half of term)
0.5 credit unit
Prerequisites: EPID 510 or equivalent and EPID 526 or equivalent, and permission of instructor

Instructor: Yimei Li, PhD
This course will focus on the specialized issues related to the analysis of survival or time-to-event data. The course begins by closely examining the features unique to survival data which distinguishes these data from other more familiar types. Topics include non-parametric survival analysis methods, common survival functions, parametric survival models, the proportional hazards model, and common model checking methods. All methods will be illustrated by in class examples and homework sets.

 

EPID 624: Methods in Patient Center Outcomes and Effectiveness Research
Spring term
1 credit unit
Prerequisites: EPID 510 or equivalent and EPID 526 or equivalent
Instructor:
Joel Gelfand, MD, MSCE
The goal of this course is to provide a broad overview to methods used in patient centered outcomes and effectiveness research. Expert faculty will lecture on topics such as standards for research questions, systematic reviews, patient/stakeholder engagement, causal inference, heterogeneity of treatment effect, handling missing data, data registries, pragmatic trials, diagnostic tests, health care disparities, evaluating the impact of communication interventions, and testing innovations in health care systems. Grading will largely be based on participation in class discussions.

 

EPID 630 - Clinical Trials
Spring term
1 course unit
Prerequisite: EPID 510 or equivalent and EPID 526 or equivalent, and permission of instructor

Instructor:Angela DeMichele, MD, MSCE
This course is to serve as a general introduction to clinical trials. This course will emphasize trial design issues. This is not a course on the biostatistics of clinical trials. It is expected that at the conclusion of the course, a student will be able to plan a clinical trial. Each class will consist of a two-hour lecture followed by a one-hour discussion. The weekly session will focus on either a group discussion of the assigned reading or on a practical application based on the material presented during the two-hour lecture.

 

EPID 632 - Medical Informatics
Summer term (Please check with Department as this course is not offered every year)
1 course unit
Prerequisite: Permission of instructor

Instructor: John Holmes, PhD
This course is designed to provide an overview of the major topic areas in medical informatics, especially as they apply to clinical research, and more specifically to clinical epidemiology. Through a series of lectures and demonstrations, students will learn about topics such as databases, natural language, clinical information systems, networks, artificial intelligence and machine learning applications, decision support, imaging and graphics, and the use of computers in medical education.

 

EPID 634 - Clinical Trial Outcomes: Measurement, Analysis, and Interpretation
Fall term
1 course unit
Prerequisite: EPID 510 or equivalent and permission of instructor

Instructor: John Farrar, MD, PhD
This course is intended to teach students the skills necessary to select and/or design appropriate outcomes for a clinical trial. Students will focus on recent changes in our understanding of clinical trial outcome measurements, analyses, and interpretation for both subjective and objective phenomenon, such as adherence, use of multiple outcomes, and clinical importance. While design issues for clinical trials are the main focus, other types of clinical studies will be considered as appropriate. Students will be expected to learn about the problems inherent in the design of outcome measures of health and how to apply different epidemiologic and biostatistical concepts toward a solution. It is expected that at the conclusion of the course, students will be able to plan a clinical trial with a valid, responsive and interpretable outcome.

 

EPID 636 - Epidemiology Methods of Acute Care
Spring Term (Please check with Department as this course is not offered every year)
1 course unit
Prerequisite: EP 510 or equivalent and permission of instructor
Instructor:
Brendan G. Carr, MD, MA, MSHP and Cynthia Mollen, MD, MSCE
This is an advanced course addressing epidemiological issues as they apply to important clinical topics in acute care, including emergency, hospital, and critical care medicine. Lectures and discussions will have two primary goals: 1) to explore epidemiologic methods specific to acute care settings (i.e., choice of outcomes, risk adjustment); and 2) to explore the epidemiology of particular diseases (e.g., sepsis, acute lung injury, hospital acquired infections) and research questions of current importance in these areas. This course will acquaint students with the classic literature in the field of adult and pediatric urgent care, emergency medicine, and critical care epidemiology, teach advanced epidemiological principles using a problem-based approach, and demonstrate the strengths and weaknesses of epidemiological research methodologies as they have been applied to acute care.

 

EPID 638 – Topics in Clinical Trial Design and Analysis
Fall Term
1 course unit
Prerequisite: EPID 630 or equivalent, and permission of instructor

Instructors: Susan Ellenberg, PhD
This course is intended to follow, and be complementary to EPID 630: Clinical Trials. It will build on the basic principles of design, conduct, and analysis introduced in that course and will go into more detail on particular approaches. Topics covered will include noninferiority trials, phase 1 designs, multi-stage and other adaptive designs, graphical data presentations and current ethical controversies in clinical trials.

 

EPID 640 - Advanced Topics in Epidemiology
Spring Term
1 course unit
Prerequisite: EPID 510 or equivalent, EPID 526 or equivalent, EPID 527 or equivalent, and permission of instructor

Instructors: Gregory P. Bisson, MD, MSCE
This course is designed to introduce students to advanced epidemiologic methods through a series of readings and discussions. The course aims to deepen the students' understanding of important concepts and controversies in contemporary epidemiology and to enhance their ability to think critically about empirical epidemiologic research. The course is intended for students who already are familiar with the fundamentals of epidemiology and biostatistics, and who wish to gain an understanding of the complex issues underlying epidemiologic study design and interpretation. Each week, one student will be responsible for leading a portion of the discussion of the assigned readings, in conjunction with a faculty member. Topics include: causal inference; study designs; use of large databases for research; predicting outcomes; and complex sampling methods.

 

EPID 644 - Cardiopulmonary Epidemiology
Summer II term (Please check with Department as this course may not offered every year)
1 course unit
Prerequisite: EPID 510 or equivalent, EPID 526 or equivalent, and permission of instructor

Instructor: Stephen Kimmel, MD, MSCE
This is an advanced course that addresses epidemiological research issues as they apply to important clinical topics in cardiovascular and pulmonary medicine. Lectures and workshops are designed to acquaint students with the classic literature in the fields of cardiovascular and pulmonary epidemiology, to use a body of literature to demonstrate the strengths and weaknesses of epidemiological research designs as they have been applied to cardiovascular and pulmonary medicine, to expose students to the range of topics studied, to teach advanced epidemiological principles using a problem-based approach, and to stimulate students to develop independent research questions.

 

EPID 645- Cancer Epidemiology, Biomarkers, and Prevention
Summer I Term (Please check with Department as this course is not offered every year)
1 course unit
Prerequisite: EPID 510 or equivalent, EPID 526 or equivalent, EPID 527 or equivalent, and permission of instructor

Instructors: Kathryn Schmitz, PhD, MPH
Research in cancer etiology, prevention, treatment, and control includes a wide range of subject matter science, from the initial molecular changes which precede the development of cancer to issues of primary care guidelines for cancer survivors. The course reviews the possible study designs applied to cancer etiology, prevention, treatment, and control. These include randomized controlled trials and multiple types of observational studies (cohort, case-control, cross-sectional). Other topics will include causal inference, bias, and effect modification.

 

EPID 646 - Reproductive Epidemiology
Spring term (Please check with Department as this course is not offered every year)
1 course unit
Prerequisite: EPID 510 or equivalent, EPID 526 or equivalent, EPID 527 or equivalent, and permission of instructor

Instructor: Kurt Barnhart, MD, MSCE
This is an advanced course that addresses epidemiological research issues as they apply to important clinical topics in obstetrics and gynecology and related clinical disciplines. Lectures and workshops are designed to acquaint students with seminal issues in the field of reproductive epidemiology, to use a body of literature to demonstrate the strengths and weaknesses of epidemiological research designs as they have been applied to obstetrics and gynecology and related clinical disciplines, to expose students to the range of topics studied, to teach advanced epidemiologic principles using a problem-based approach, and to stimulate students interested in reproductive epidemiology to develop independent research questions.

 

EPID 652 - Renal and Urologic Epidemiology
Summer I Term (Please check with Department as this course is not offered every year)
1 course unit
Prerequisite: EP 510 or equivalent, EPID 526 or equivalent, EPID 527 or equivalent, and permission of instructor

Instructors: Harold I. Feldman, MD, MSCE and Amanda Anderson, PhD, MPH
The objective of this course is to prepare students to function as effective, independent researchers in the fields of renal and urologic epidemiology by providing the students an understanding of how epidemiologic research can and has advanced the knowledge of diseases in treatments of renal and urologic medicine. The structure of the course consists of a lecture series, accompanying workshops, and student presentations. The courses goals are: to acquaint students with some of the classic literature in the fields of renal and urologic epidemiology, to use a body of literature to demonstrate the strengths and weaknesses of epidemiologic research designs as they have been applied to renal and urologic medicine, to teach advanced epidemiologic principles using a problem-based approach, and to expose students to the rationale of topics studied by faculty in the CCEB and the adult and pediatric nephrology and urology divisions at Penn and CHOP.

 

EPID 656 - Epidemiological Research Methods in Infectious Diseases
Summer I term (Please check with Department as this course is not offered every year)
1 course unit
Prerequisite: EPID 510 or equivalent, EPID 526 or equivalent, a course that covers logistical regression, such as EPID 527 or equivalent, and permission of instructor

Instructors: Ebbing Lautenbach, MD, MPH and Robert Gross, MD, MSCE
This will be an advanced course addressing epidemiological issues as they apply to important clinical topics in infectious diseases. Lectures and discussions will serve two primary goals: 1) to explore epidemiologic methods specific to infectious diseases (e.g., adherence to therapy) or which have important applications to infectious diseases (e.g., molecular epidemiology); and 2) to explore the epidemiology of particular infectious diseases or syndromes (e.g., HIV). This course will acquaint students with the classic literature in the field of infectious diseases epidemiology, teach advanced epidemiological principles using a problem-based approach, and demonstrate the strengths and weaknesses of research methodologies as they have been applied to infectious diseases.

 

EPID 658 - GI Epidemiology
Spring Term (Please check with Department as this course is not offered every year)
1 course unit
Prerequisite:
EPID 510 or equivalent
Instructors: Yi-Xiao Yang, MD, MSCE
This course provides an in-depth presentation of advanced methodological issues in conducting clinical epidemiological research in the field of gastroenterology.

 

EPID 664 - Methods in Neurologic Clinical Epidemiology
Spring term (Please check with Department as this course is not offered every year)
0.5 course unit
Prerequisite:
Permission of instructor
Instructors: John Farrar, MD, PhD
This course/ seminar will introduce students to methods and study design principles that are specific or unique to clinical research and trials in neurology, child neurology, neuro-ophthalmology, neurosurgery, and related fields.

 

EPID 666 - Pharmacoepidemiology Research
Spring Term
1 course unit
Prerequisite: EPID 510 or equivalent; EPID 526 or equivalent; a course that covers logistic regression, such as EPID 527 or equivalent; and permission of instructor

Instructor: Sean Hennessy, PharmD, PhD
The purpose of this course is to explore and integrate concepts and considerations that are key to the conduct of pharmacoepidemiologic research. The format will be a mixture of seminar, instructor-led discussion, student-led discussion, and student presentations. Papers from the applied and methods literature will be used to illustrate concepts and as springboards for discussion. Topics covered include use of automated databases, pharmacogenomics, and approaches to addressing confounding.

 

EPID 672: Biostatistical Methods for the Pharmacoepidemiologist
Summer I term
1 course unit
Prerequisite: EPID 510 or equivalent; EPID 526 or equivalent; EPID 527 or equivalent; and permission of instructor
Instructors:
Jason Roy, PhD and Alexis Ogdie-Beatty, MD, MSCE
This course is designed to teach epidemiology students the statistical principles of analysis specific to pharmacoepidemiology study designs including the use of propensity scores, inverse probability weighting, instrumental variables and time varying covariates. Each of the twelve sessions includes both a lecture component and a laboratory component. Students will learn the statistical principles and then apply them to example study datasets. Laboratory sessions will be conducted on students’ laptops using STATA software.

 

EPID 675 - Advanced Methods for Analysis of Complex Genetic Traits
Fall term  (Please check with Department as this course is not offered every year)
1 course unit
Prerequisite: EPID 575 or equivalent; Linear Models, Multivariate Analysis preferred; and permission of instructor

Instructors: Timothy Rebbeck, PhD and Danish Saleheen, PhD
The recent explosion in the availability of molecular level data coupled with technological advancements allowing for large-scale sequencing creates an exciting opportunity to tailor treatment decisions to the specific genetic characteristics of a patient. Epidemiological studies will provide the tools to draw from this vast array of molecular data as well as well-established environmental risk factors to predict disease outcomes. However, understanding analytic methods for characterizing the complex interactions among genetic polymorphisms, biomarkers, environmental factors, and disease outcomes is imperative to draw meaningful and relevant conclusions from these studies. Through this course, students will understand and present advanced statistical methods and how they can be applied to the study of complex genetics traits.

 

EPID 690 - Empirical Bioethics
Spring term (Please check with Department as this course is not offered every year)
1 course unit
Prerequisite: Permission of instructor

Instructors: Scott Halpern, MD, PhD and Peter Reese, MD, MSCE
Solutions to many of the most pressing problems in modern bioethics require empirically testing assumptions and theories about human behaviors and attitudes. This course will use papers from the primary literature to teach students to understand and use the many methods that have been or could be employed to address questions lying at the intersection of ethics and clinical research. In addition to participating in weekly discussions of these topical and methodological papers, students will be expected to develop and present a protocol for research designed to explore ethical dilemmas within their own disciplines.

 

EPID 700 - Doctoral Seminar in Epidemiology
Spring and Fall terms
0.5 course unit
Prerequisite: Permission of Instructor, Candidates for the PhD Degree in Epidemiology only

Instructor: John Holmes, PhD
This course is intended to meet the needs of PhD students over the entire program, from the coursework phase through the dissertation defense, and is intended to optimize cross-fertilization between the students at all phases of their program. An overarching theme of the seminar is the development of professionalism.

 

EPID 710 - Research Design Consultation
Fall, Spring, and Summer terms
1 course unit
Consultation Service, meeting times TBA
Prerequisite: Candidates for the PhD Degree in Epidemiology only

Instructor: John Holmes, PhD
Students will devote at least 100 hours working with faculty on projects related to the Center for Clinical Epidemiology and Biostatistics' Consultation Service or on other projects as approved by the course director.  The goal of this course is to provide real-world consulting experience for doctoral students.  Accordingly, the requirements for the course cannot be met by serving as a teaching assistant or working in the role of an analyst or other project staff.

 

EPID 714 – Grant Writing
Summer II Term
0.5 course unit
Prerequisite: EPID 510, EPID 526, EPID 560, and EPID 570, or permission of instructor

Instructor: John Farrar, MD, PhD
This course is designed to provide background and guidance on writing and submitting NIH grants. Students will submit a mini proposal at the beginning of the term. Each proposal will be reviewed by a group of 3 students from the class and scores will be given. The final project will be a full NIH proposal ready for submission.

 

EPID 721 - Longitudinal and Clustered Data in Epidemiologic Research, Advanced Topics
Spring term (Please check with Department as this course is not offered every year)
1 course unit
Prerequisite: EPID 621 or a class in longitudinal data at the graduate level. Permission of instructor

Instructors: A. Russell Localio, PhD and Marshall M. Joffe, PhD
Advanced methods for longitudinal and clustered data analysis with special emphasis on formal principles of causal inference, analysis of complex samples from surveys, use of Monte Carlo methods of estimation, and methods for adjusting for missing data and dropout, with applications in epidemiology, social sciences, and public health.

 

EPID 775 - Special Topics in Genetic and Molecular Epidemiology
Term TBA
1 course unit
Meeting times are arranged
Prerequisite: EPID 575 or equivalent, EPID 675 or equivalent, and permission of instructor

Instructor: Timothy Rebbeck, PhD
This modular course meets the needs of students who require specialized instruction and hands-on training in specific topics that are not available in a traditional course setting. Multiple modules are available, providing advanced training in specific methods in genetic and molecular epidemiology, including the possibility of laboratory rotations to obtain hands-on laboratory experience. Each student may choose up to four modules for study during the semester-long course. Each module includes readings, meetings with faculty, problem sets, laboratory analysis, or analysis of data, as appropriate.

 

EPID 900 - Master Thesis
Fall, Spring, and Summer terms
0.5 to 4 course units
Prerequisite: Candidates for the Masters in Clinical Epidemiology degree only

Instructor: CCEB faculty
These are a series of tutorial sessions conducted by the student's advisor, which are to support the student's efforts in developing a research protocol, designing a research project, and completing the study.

 

EPID 999 - Independent Study in Clinical Epidemiology
Fall, Spring, and Summer terms
0.5 to 4 course units
Maximum enrollment: unlimited
Prerequisite: Permission of faculty required

Instructor: CCEB faculty
This is a preceptorship that can be arranged with any of the CCEB faculty. The subject area and specific requirements are to be arranged as well.

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