Master of Science in Clinical Epidemiology (MSCE)
The Master of Science in Clinical Epidemiology (MSCE) degree program provides comprehensive clinical research training. The goal of the program is to train individuals for successful careers as independent investigators. This program is directed by the faculty of the Center for Clinical Epidemiology and Biostatistics. The School of Medicine's Office of Research and Research Training has oversight responsibilities for the program and the MSCE degree is awarded by the University of Pennsylvania School of Medicine.Admissions
Admissions requirements for the Master of Science in Clinical Epidemiology (MSCE) degree reflect the emphasis on integrating epidemiology and clinical practice. Individuals admitted into either program must have an advanced degree in medicine, nursing, or another health-related field, from an accredited college or university. The Admissions page includes details about requirements and procedures for applying to the epidemiology degree programs.Faculty Mentor
Students enrolled in the MSCE degree program are assigned to a faculty mentor based on the student's research interest. The mentor will act in an advisory capacity throughout that student's course of study, particularly regarding the development of the required research project.Core Courses
All students are required to complete a required core of courses, generally taken in the first year of study:- Introductory Epidemiology (EP 510)
- Introductory Biostatistics (EP 520)
- Statistical Methods for Epidemiologic Research (EP 521)
- Database Management for Clinical Epidemiology (EP 532)
- Measurement of Health in Epidemiology (EP 542)
- Issues in Research Protocol Development (EP 560)
- Critical Appraisal of the Medical Literature (EP 570)
- Tutorial in Epidemiologic Research (EP 610)
- Introductory Epidemiology
- Introductory Biostatistics
- Database Management for Clinical Epidemiology.
Additional courses are required, some of which may be electives, depending on the Track in which the student is enrolled.
Non-credit Requirements
Students also are required to participate in a series of programs for which credits are not awarded. These requirements include: participation for at least one year in the weekly CCEB Research Seminar, which runs from September through June annually; completion of an online seminar on the ethics of biomedical research; and completion of the School of Medicine's online Patient Oriented Certification Program.Tracks
Upon enrollment, students will choose one of five Tracks, based on research interests: Epidemiology, Health Services Research, Human Genetics, Bioethics, or Clinical Trials. The required core of courses is the same for each Track. Additional elective or Track-specific required courses are taken in addition to the core courses to provide the proper foundation for each Track.Electives
Students may choose electives from advanced courses in epidemiology, biostatistics, computer sciences, or other related fields. See Epidemiology Course Descriptions for descriptions of all epidemiology courses offered by the CCEB. They also may arrange to take one or more independent study courses taught by members of the CCEB faculty or one or more courses taught elsewhere in the University.All electives will be chosen in consultation with the student's faculty advisor and must be approved by the advisor and, as needed, by the Academic Director of the MSCE Degree Program.
It also is possible to take courses at other institutions, pending approval of the Academic Director and the student's advisor. Official transcripts are required for all courses taken elsewhere. Course units will be assigned to those courses based on University guidelines. No work done as an undergraduate will be counted as credit toward this degree.
Comprehensive Examination
After all core requirements have been successfully completed, students are required to sit for the MSCE Program Comprehensive Examination. It is given at the end of May each year and is typically taken after the first year of coursework.The Examination is administered in an eight-hour examination. It is designed to assess the following: the student's understanding of epidemiologic concepts; elements of research methods; ability to design studies to address specific research questions; analysis of straightforward statistical problems using a small data set; facility with reading and interpreting computer printouts of statistical analyses; and ability to review critically the medical literature.
Thesis
A student is expected to design a research project, write a formal research protocol, perform the study described in it, and prepare a comprehensive scholarly scientific paper reporting the results. Students present their thesis protocols at a special session of the CCEB Research Seminar.It is anticipated that the thesis will be relevant to the student's Track and will address a question of importance in the student's clinical field. The thesis should be written in the format of a journal article and should be acceptable for submission to a journal. The thesis must be accepted by the student's thesis committee, consisting of his or her advisor and two other faculty.
Graduation
Upon completion of degree requirements, candidates are expected to complete a "graduation application" approximately three months prior to the expected graduation date. Submission of the graduation application will be coordinated with the MSCE Educational Programs Office. The application initiates an academic audit conducted by the MSCE Educational Programs Office. The MSCE degree is conferred by the University of Pennsylvania School of Medicine. Graduation occurs in May and December annually.By graduation, students will have obtained the following skills:
- knowledge of elements of research design, including randomized clinical trials, cohort and case-control studies, surveys and quasi-experiments
- detailed and in depth facility with one of the designs listed above, the one which will be used in the research protocol
- knowledge of the concepts of health measurement as applied to epidemiologic research
- ability to critically appraise the medical literature
- in-depth familiarity with the principles of biostatistics, especially as they apply to epidemiologic and health services research
- ability to use and interpret a variety of PC-based statistical programs for analyzing a data set
- ability to design, implement and analyze a research project
