Pulmonary and Critical Care Epidemiology

Program Description

The Pulmonary and Critical Care Epidemiology Program at Penn includes funded research in several major diverse areas of pulmonary diseases and critical illness, including lung transplantation, Acute Lung Injury (ALI) and Acute Respiratory Distress syndrome (ARDS), sepsis, chronic critical illness, asthma, Chronic Obstructive Pulmonary Disease (COPD), sleep disorders, pulmonary vascular disease, right ventricular structure and function, smoking cessation, and lung cancer. Methodological areas include clinical and genetic epidemiology, proteomics, genomics, medication adherence, improvement of clinical trial design, long term outcomes of critical illness, imaging, clinical trials of novel therapeutics, behavioral economics, and cancer screening. A transdisciplinary program in critical care health services research and medical ethics, including investigators from the School of Medicine and Whorton School, integrates seamlessly with the epidemiology program. Ongoing pulmonary studies include investigatons of large numbers of well characterized patients with ALI, lung transplantation, right ventricular assessment, lung cancer, mesothelioma, and idiopathic pneumonias. Areas of specialization in the critical care setting include the diagnosis and management of sepsis and its complications, traumatic injury and subsequent organ dysfunction, improvements in critical care procedural safety, defining meaningful outcomes for use in critical care clinical trials, defining quality metrics in the ICU, cost-effectiveness research, ICU staffing models, end-of-life decision-making, and the rationing of critical care.

Training grants focused on the genetics of lung disease, vascular medicine, thrombosis, cardiopulmonary epidemiology, pharmacoepidemiology, neuroepidemiology, and critical care health policy research are available to support fellows during training.

Program Members

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