Faculty

Alanna Strong, MD, PhD

Assistant Professor of Pediatrics (Human Genetics)

Department: Pediatrics

Graduate Group Affiliations

Cell and Molecular Biology

Contact information

Children's Hospital of Philadelphia
Division of Human Genetics
3615 Civic Center Blvd
Abramson Research Center, Room 1016D
Philadelphia, PA 19104

Office: 267-582-0429

Email:
strong.alanna@gmail.com

Education:
BA (Biology)
University of Pennsylvania, 2005.
PhD (Cellular and Molecular Biology)
University of Pennsylvania, 2012.
MD
University of Pennsylvania, 2014.

Permanent link

> Perelman School of Medicine > Faculty > Details

Description of Clinical Expertise

Genetics, genetic liver diseases, genetic kidney diseases, ciliopathy

Description of Research Expertise

Ciliopathy, cilium, hepatobiliary disease, kidney disease

Selected Publications

Grady LO, Zoltick ES, Zouk H, He W, Perez E, Clarke L, Gold J, Strong A, Sahai I, Yeo J, Green RC, Karaa A, Gold NB : Long-Term Health Outcomes of Individuals With Pseudodeficiency Alleles in IDUA May Inform Newborn Screening Practices for Mucopolysaccharidosis Type I. American Journal Med Genet A 197(4): e63940, Apr 2025 Notes: doi: 10.1002/ajmg.a.63940. Epub 2024 Nov 19.

Cardinale CJ, Liu Y, Kevadia A, Strong A, Watts VJ, Hakonarson H: The ulcerative colitis risk gene adenylyl cyclase 7 restrains the T helper 2 phenotype and Class II antigen presentation. J Crohns Colitis 19(3): jjaf030, Mar 2025 Notes: doi: 10.1093/ecco-jcc/jjaf030.

Marshall RF, Landau-Prat D, Strong A, Katowitz JA, Katowitz WR. : Ocular and Systemic Abnormalities in Punctal Agenesis. Ophthalmic Plast Reconstr Surg 41(2): 209-212, Mar-Apr 2025 Notes: doi: 10.1097/IOP.0000000000002789. Epub 2024 Oct 8.

Pingault V, Neiva-Vaz C, de Oliveira J, Martínez-Gil N, Lasa-Aranzasti A, Campos B, Lakeman IMM, Nibbeling EAR, Stoeva R, Jayakar P, Dabir T, Elloumi HZ, Strong A, Hanein S, Picard A, Ochsenbein F, Blanc P, Amiel J : Chromatin assembly factor subunit CHAF1A as a monogenic cause for oculo-auriculo-vertebral spectrum. European Journal of Human Genetics 33(1): 131-136, Jan 2025 Notes: doi: 10.1038/s41431-024-01698-5.

Watson D, Mentch F, Billings J, Ostberg K, March ME, Kalish JM, Li D, Cannon I, Guay-Woodford LM, Hartung E, Strong, A. : Elucidating the Molecular Landscape of Cystic Kidney Disease: Old Friends, New Friends and Some Surprises. Am J Med Genet A Page: e64011, Jan 2025 Notes: doi: 10.1002/ajmg.a.64011. Online ahead of print.

Gold JI, Strong A, Gold NB, Yudkoff M, Szalda D, Jan S, Schwartz LA, Ganetzky R: Executive and adaptive function impacts long-term outcomes for adults with maple syrup urine disease. Journal of Inherited Metabolic Disease 48(1): e12827, Jan 2025 Notes: doi: 10.1002/jimd.12827. Epub 2024 Dec 10.

Saeidian AH, March ME, Youssefian L, Watson DJ, Bhandari E, Wang X, Zhao X, Owen NM, Strong A, Harr MH, CAG Secondary Finding Consortium, Bhoj E, Zackai EH, Vahidnezhad H, Gudjonsson JE, Cederbaum SD, Deignan JL, Glessner J, Grody WW, Hakonarson, H: Secondary ACMG and non-ACMG genetic findings in a multiethnic cohort of 16,713 pediatric participants. Genetics In Medicine 26(11): 101225, Nov 2024 Notes: doi: 10.1016/j.gim.2024.101225. Epub 2024 Jul 31.

Smal N, Majdoub F, Janssens K, Reyniers E, Meuwissen MEC, Ceulemans B, Northrup H, Hill JB, Liu L, Errichiello E, Gana S, Strong A, Rohena L, Franciskovich R, Murali CN, Huybrechs A, Sulem T, Fridriksdottir R, Sulem P, Stefansson K, … Weckhuysen S. : Burden re-analysis of neurodevelopmental disorder cohorts for prioritization of candidate genes. European Journal of Human Genetics 32(11): 1378-1386, Nov 2024 Notes: doi: 10.1038/s41431-024-01661-4. Epub 2024 Jul 4.

Strong A, March ME, Cardinale CJ, Liu Y, Battig MR, Finoti LS, Matsuoka LS, Watson D, Sridhar S, Jarrett JF, Cannon I, Li D, Bhoj E, Zackai EH, Rand EB, Wenger T, Lerman BB, Shikany A, Weaver KN, Hakonarson H.: Novel insights into the phenotypic spectrum and pathogenesis of Hardikar syndrome. Genetics In Medicine 26(10): 101222, Oct 2024 Notes: doi: 10.1016/j.gim.2024.101222. Epub 2024 Jul 20.

Landau-Prat D, Marshall R, Strong A, Katowitz JA, Katowitz WR: Punctal Atresia As a Clinical Indicator of Systemic Genetic Anomalies. Semin Ophthalmol. Page: 1-4, April 2024 Notes: doi: 10.1080/08820538.2024.2345291. Online ahead of print.