Faculty
Paul J Planet, Ph.D, M.D.

Assistant Professor of Pediatrics (Infectious Diseases)
Department: Pediatrics
Graduate Group Affiliations
Contact information
Children's Hospital of Philadelphia
3615 Civic Center Blvd
Abramson 1202A
Philadelphia, PA 19104
3615 Civic Center Blvd
Abramson 1202A
Philadelphia, PA 19104
Office: 9175140695
Email:
planetp@chop.edu
planetp@chop.edu
Publications
Education:
BS (Molecular Biophysics & Biochemistry and Anthropology)
Yale University, 1996.
Ph.D (Integrated Program for Cellular, Molecular, and Biophysical Studies)
Columbia University College of Physicians & Surgeons, 2003.
MD
Columbia University College of Physicians & Surgeons, 2004.
Permanent linkBS (Molecular Biophysics & Biochemistry and Anthropology)
Yale University, 1996.
Ph.D (Integrated Program for Cellular, Molecular, and Biophysical Studies)
Columbia University College of Physicians & Surgeons, 2003.
MD
Columbia University College of Physicians & Surgeons, 2004.
Description of Clinical Expertise
Dr. Planet is a pediatric infectious disease specialist. Dr. Planet has specific areas of interest in antibiotic resistant infections (MRSA), respiratory infections, and chronic infections in patients with cystic fibrosis.Description of Other Expertise
Evolution of SARS-CoV-2Description of Research Expertise
Paul J. Planet MD, PhD is an Assistant Professor of Pediatrics at the Children’s Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania. He is also a senior researcher at the American Museum of Natural History.Dr. Planet graduated from Yale University with a Bachelors degree in Anthropology and Molecular Biochemistry & Biophysics. He went on to earn his MD and PhD from Columbia University, where he also completed his residency and fellowship training at the Children’s Hospital of New York. His first faculty appointment was in the division of Pediatric Infectious Disease at Columbia University.
Dr. Planet’s research program focuses on the evolution and ecology of infectious disease. His current interests include the evolution and spread of antibiotic resistant strains, particularly community acquired MRSA, and the impact of the pulmonary microbiome in cystic fibrosis. Dr. Planet’s laboratory uses whole genome phylogenetics, high-throughput sequencing, and bioinformatics to generate hypotheses that are then tested with bench-based microbiology and molecular techniques.
Selected Publications
West SR, Adekoya AE, Arriaga SK, Rajagopol S, Varriale SL, Planet PJ, Ibberson CB: Genomic analysis of eight clinical Rothia isolates. Microbiol Resour Announc August 2025.Chen YT, Liu Z, Fucich D, Giulieri SG, Liu Z, Wadhwa R, Rios G, Henschel H, Tyagi N, Olivier FAB, Monk IR, Shah SS, Sridhar SH, Drikic M, Bianco C, Lohia GK, Beg AZ, Planet PJ, Lewis IA, Sebra R, Traven A, Hachani A, Stinear TP, Howden BP, Boyd JM, Riquelme SA, Wang C, Prince A, Wong Fok Lung T. : Regulation of airway fumarate by host and pathogen promotes Staphylococcus aureus pneumonia. Nat Commun 16(1), August 2025.
Free M, Soper N, Slaughter JC, Feder A, Bianco C, Moustafa AM, Planet P, Creech CB, Thomsen I.: Evolution of strain diversity and virulence factor repertoire in pediatric Staphylococcus aureus isolates. PLoS One 20(7), July 2025.
Brazer N, Servellita V, Jin C, Foresythe A, Oseguera M, Nguyen J, Sumimoto N, Huh HJ, Feder A, Bhattacharya S, Bhaskar S, Sotomayor-Gonzalez A, Saldhi P, Choi C, Li GX, Gopchandani K, Tippett A, Hsiao HM, Gonzalez MD, Gulick D, Kraft C, Kasinathan V, Wang YFW, Chen PY, Flores-Vazquez J, Patel K, Odom John AR, Spinler JK, Devaraj S, Annapragada AV, Luna RA, Gai X, Dien Bard J, Rostad CA, Planet PJ, Lazar AA, Chiu CY: Differential severity of SARS-CoV-2 variant infections in children and adults with COVID-19. J Clin Virol 180, July 2025.
Piteková B, Hric I, Baranovičová E, Zieg J, Planet PJ, Bielik V. : The effect of fecal microbial transplantation in a pediatric patient after 28 episodes of febrile urinary tract infection. Pediatr Nephrol. Page: doi: 10.1007/s00467-025-06822-1, Jun 2025 Notes: epub ahead of print.
Piteková B, Hric I, Zieg J, Baranovičová E, Konopásek P, Gécz J, Planet PJ, Bielik V.: The gut microbiome and metabolome in children with a first febrile urinary tract infection: a pilot study. Pediatr Nephrol. Page: doi: 10.1007/s00467-025-06782-6, May 2025 Notes: epub ahead of print.
Sun Y, Hu B, Chhabra S, Tolentino J, Suzuki N, Natarajan J, Harris Z, Stanley G, Bianco C, Planet P, Sherchand SP, Adhikari R, Aman J, Zhang X, Koff J, Rajagopalan G.: Prevalence, Production and the Role of Staphylococcus aureus Superantigens in Cystic Fibrosis Lung Disease. bioRxiv May 2025.
Esteves, MAC, Carvalho, MF, Viana, AS, Martini, CL, Longo, LGA, Silva, DNS, Ferreira, ALP, Ferreira-Carvalho, BT, Planet, PJ, Figueiredo, AMS: Decoding the evolutionary history of ST30 Staphylococcus aureus: insights into a potentially silent MSSA bloodstream pathogen. Frontiers in Microbiology 16(1): 1522747, April 2025.
Martínez JRW, Alcalde-Rico M, Jara-Videla E, Reyes J, Carvajal LP, Rincon S, Ríos R, Diaz L, Quesille-Villalobos A, Riquelme-Neira R, Rivas L, Moustafa AM, Hanson B, Undurraga EA, Olivares-Pacheco J, García P, Araos R, Planet PJ, Arias CA, Munita JM: Geographic divergence of methicillin-resistant Staphylococcus aureus ST5-SCCmecI in the aftermath of a major earthquake and tsunami: impact of a plasmid harboring heavy metal resistance genes. MBio 16(4): e0366924, April 2025.
Hecht AL, Mahmud N, Chaudhry S, Cao JY, Branigan GP, Lee J, Theiller E, Roggiani M, Friedman ES, Herman L, Galis BE, Jones SM, Planet PJ, Zackular JP, Kaplan DE, Serper M, Rajender Reddy K, Moustafa AM, Goulian M, Wu GD: Carbohydrate consumption drives adaptive mutations in Escherichia coli associated with increased risk for systemic infection. bioRxiv March 2025 Notes: doi: 10.1101/2025.03.26.645536.
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