Faculty
Ewa Bomba-Warczak, Ph.D.

Assistant Professor of Physiology
Department: Physiology
Graduate Group Affiliations
Contact information
University of Pennsylvania, Department of Physiology
626 Clinical Research Building
415 Curie Boulevard
Philadelphia, PA 19104
Philadelphia, PA 19014
626 Clinical Research Building
415 Curie Boulevard
Philadelphia, PA 19104
Philadelphia, PA 19014
Publications
Education:
BS (Biological Sciences, w/honors)
University of Illinois at Chicago, 2010.
PhD (Neuroscience)
University of Wisconsin – Madison, 2016.
Permanent linkBS (Biological Sciences, w/honors)
University of Illinois at Chicago, 2010.
PhD (Neuroscience)
University of Wisconsin – Madison, 2016.
Selected Publications
Bomba-Warczak E., Savas JN: Long-lived mitochondrial cristae proteins in mouse heart and brain. American Society of Cell Biology 2023 Notes: Poster presentation at Cell Bio 23: ASCB and EMBO meeting, Boston, MA (December 2-6, 2023).Bomba-Warczak E., Velez K., Zhou L., Guillermier C., Edassery S., Steinhauser M., Savas J., Duncan F.: Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan. bioRxiv 2023.10.18.562852; doi: https://doi.org/10.1101/2023.10.18.562852 (Accepted at eLife) 2023.
Bomba-Warczak E., Savas JN: Long-lived proteins as drivers of neuronal aging. Keystone Conference. March, 24 2023 2023 Notes: Poster Presentation at Keystone Mitochondrial Dysfunction: From Ultra-Rare Diseases to Aging, Breckenridge CO.
Ramirez MA, Ninoyu Y, Miller C, Andrade LR, Edassery S, Bomba-Warczak E., Ortega B, Manor U, Rutherford MA, Friedman RA, Savas JN: Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3. iScience. 2022 Jul 20;25(8):104803. doi: 10.1016/j.isci.2022.104803 2022.
Bomba-Warczak E., Savas JN: Long-lived mitochondrial proteins and why they exist Trends in Cell Biology. 2022 Aug;32(8):646-654. doi: 10.1016/j.tcb.2022.02.001. 2022.
Pegg, C.E., Zaichick, S.V., Bomba-Warczak, E., Jovasevic, V., Kim D.H., Kharkwal, H., Wilson, D. W., Walsh, D., Sollars, P.J., Pickard, G.E., Savas, J.S., Smith G. A. : Herpesviruses assimilate kinesin to produce motorized viral particles. Nature 599, 662–666 (2021). doi.org/10.1038/s41586-021-04106-w 2022.
Bomba-Warczak E., Hark TJ., Edassey SL., Savas JN: Long-lived mitochondrial proteins in mouse heart and brain. J Cell Biol (2021) 220 (9): e202005193; doi: 10.1083/jcb.202005193 2021.
Hark TJ, Rao NR, Castillon C, Basta T, Smukowski S, Bao H, Upadhyay A, Bomba-Warczak E., Nomura T, O'Toole ET, Morgan GP, Ali L, Saito T, Guillermier C, Saido TC, Steinhauser ML, Stowell MHB, Chapman ER, Contractor A, Savas JN: Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer's Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals Cell Syst. 2021 Feb 17;12(2):141- 158.e9. doi: 10.1016/j.cels.2020.11.007 2021.
Bomba-Warczak E. Hark T., Edassery S. Savas JN: Exceptionally long-lived proteins as pillars of mitochondrial architecture in the aging brains. Society for Neuroscience (SfN) Conference, Chicago IL 2019 Notes: Poster Presentation at Society for Neuroscience. October 19, 2019
Bomba-Warczak E. Hark T., Edassery S. Savas JN: Exceptionally long-lived proteins as pillars of mitochondrial architecture in the aging brains. Gordon Research Conference. March 23, 2019 2019 Notes: Poster presentation at Gordon Research Conference: Mitochondria in Health and Disease, Ventura CA.
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