Faculty

Yijing Su, Ph.D.

Assistant Professor of Cell and Developmental Biology

Department: Cell and Developmental Biology

Graduate Group Affiliations

Contact information

Department of Oral Medicine
School of Dental Medicine
University of Pennsylvania
Philadelphia, PA 19104

Office: 443-838-6479

Education
B.S. (Biology with a minor in Computer Science)
Nanjing University, Nanjing, China, 2004.
Ph.D. (Biochemistry)
Nanjing University, Nanjing, China, 2009.

Links
google scholar

Permanent link

> Perelman School of Medicine > Faculty > Details

Selected Publications

Zhou Y*, Su Y*, Yang Q*, Li J*, Hong Y, Gao T, Zhong Y, Ma X, jin M, Liu X, Yuan N, Kennedy B, Wang L, Yan L, Viaene A, Helbig I, Kessler S, Kleinman J, Hyde T, Nauen D, Liu C, Liu Z, Shen Z, Li C, Xu S, He J, Weinberger D, Ming GL, Song H: Cross-species analysis of adult hippocampal neurogenesis reveals human-specific gene expression but convergent biological processes. Nat Neurosci 2025.

Dunn J*, Moore C*, Kim NK*, Gao T, Cheng Z, Jin P, Ming GL, Qian J#, Su Y#, Song H#, Zhu H#. : Transcription Factor-Wide Association Studies (TF-WAS) to Identify Functional SNPs in Alzheimer's Disease. Journal of Neuroscience Dec 2024.

Yu, H, Nagi, SS, Usoskin, D, Hu, Y, Kupari, J, Bouchatta, O, Yan, H, Cranfill, SL, Gautam, M, Su, Y, Lu, Y, Wymer, J, Glanz, M, Albrecht, P, Song, H, Ming, GL, Prouty, S, Seykora, J, Wu, H, Ma, M, Marshall, A, Rice, FL, Li, M, Olausson, H, Ernfors, P, Luo, W: Leveraging deep single-soma RNA sequencing to explore the neural basis of human somatosensation. Nat Neurosci Nov 2024.

LaNoce, E, Zhang, D, Garcia-Epelboim, A, Su, Y, Sun, Y, Alepa, G, Angelucci, AR, Akay-Espinoza, C, Jordan-Sciutto, K, Song, H, Ming, GL, Christian, KM: Exposure to the antiretroviral drug dolutegravir impairs structure and neurogenesis in a forebrain organoid model of human embryonic cortical development. Frontiers in Molecular Neuroscience Nov 2024.

Chen, ZK, Quintanilla, L, Su, Y, Sheehy, RN, Simon, JM, Luo, YJ, Li, YD, Chen, Z, Asrican, B, Tart, DS, Farmer, WT, Ming, GL, Song, H, Song, J: Septo-dentate gyrus cholinergic circuits modulate function and morphogenesis of adult neural stem cells through granule cell intermediaries. Proc Natl Acad Sci U S A Oct 2024.

Zhou, Y, Su, YJ, Ming, GL, Song, HJ: Special properties of adult neurogenesis in the human hippocampus: Implications for its clinical applications. Clin Transl Med 13(2), Feb 2023.

Su Y, Zhou Y, Bennett ML, Li S, Kennedy BC, Zhang DY, Bond AM, Sun Y, Jacob F, Lu L, Hu P, Viaene AN, Helbig I, Kessler SK, Lucas T, Salinas RD, Gu X, Chen HI, Wu H, Kleinman JE, Hyde TM, Nauen DW, Weinberger DR, Song H, Ming GL.: A Single-Cell Transcriptome Atlas of Glia Diversity in theHuman 1Hippocampus across the Postnatal Lifespan. Cell Stem Cell 29(11): 1594-1610, Oct 2022.

Zhou Y, Su Y, Li S, Kennedy BC, Zhang DY, Bond AM, Sun Y, Jacob F, Lu L, Hu P, Viaene AN, Helbig I, Kessler SK, Lucas T, Salinas RD, Gu X, Chen HI, Wu H, Kleinman JE, Hyde TM, Nauen DW, Weinberger DR, Ming GL, Song H.: Molecular landscapes of human hippocampal immature neurons across lifespan. Nature Aug 2022.

Huang WK, Wong SZH, Pather SR, Nguyen PTT, Zhang F, Zhang DY, Zhang Z, Lu L, Fang W, Chen L, Fernandes A, Su Y, Song H, Ming GL.: Generation of hypothalamic arcuate organoids from human induced pluripotent stem cells. Cell Stem Cell 28: 1657-1670, Sep 2021.

Wang X, Ye F, Wen Z, Guo Z, Yu C, Huang WK, Rojas Ringeling F, Su Y, Zheng W, Zhou G, Christian KM, Song H, Zhang M, Ming GL.: Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders. Mol Psychiatry 2021.