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Richard Scott Poethig, Ph.D.
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Graduate Group Affiliations
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Contact information
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103E Lynch Bldg
3d 433 S. University Ave
Philadelphia, PA 19104-6018
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3d 433 S. University Ave
Philadelphia, PA 19104-6018
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Office: 215 898-8915
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Email:
spoethig@sas.upenn.edu
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spoethig@sas.upenn.edu
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Publications
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Education:
21 9 B.A. 14 (Biology) c
2b College of Wooster, 1974.
21 a Ph.D. 22 (Developmental Biology) c
28 Yale University, 1981.
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Permanent link21 9 B.A. 14 (Biology) c
2b College of Wooster, 1974.
21 a Ph.D. 22 (Developmental Biology) c
28 Yale University, 1981.
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49 Genetic regulation of the juvenile-to-adult transition in plants
35 The developmental function of RNAi in plants
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63 Key words: miRNA, siRNA, RNAi, developmental genetics, developmental timing, plants.
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26 Description of Research
2ce I am primarily in the mechanism of the juvenile-to-adult transition in plants. We have approached this problem by identifying and characterizing mutations that affect the timing of this transition. Interestingly, most of the genes identified in these screens regulate the biogenesis or function of miRNAs or a novel class of endogenous siRNAs we discovered, called “trans-acting siRNAs”. We are studying the function of genes involved in the biogenesis of trans-acting siRNAs, and are trying to identify the targets and developmental functions of these regulatory siRNAs. Several ta-siRNA targets of already been identified and are being studied to determine their role in the juvenile-to-adult transition.
8
20 Rotation Projects
44 1. Participate in mutant screens for phase change mutations
35 2. Positionally clone newly identified genes
5d 3. Characterize the molecular and developmental phenotype of phase change mutations.
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1e Lab personnel:
2c Stewart Gillmor, Postdoctoral Fellow
2a Mee Yeon Park, Postdoctoral Fellow
24 Mike Smith, Graduate Student
28 Dennie Tompers, Graduate Student
2d Matthew Willmann, Postdoctoral Fellow
23 Gang Wu, Postdoctoral Fellow
26 7 1d 1f
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Description of Research Expertise
2b Research Interests49 Genetic regulation of the juvenile-to-adult transition in plants
35 The developmental function of RNAi in plants
8
63 Key words: miRNA, siRNA, RNAi, developmental genetics, developmental timing, plants.
8
26 Description of Research
2ce I am primarily in the mechanism of the juvenile-to-adult transition in plants. We have approached this problem by identifying and characterizing mutations that affect the timing of this transition. Interestingly, most of the genes identified in these screens regulate the biogenesis or function of miRNAs or a novel class of endogenous siRNAs we discovered, called “trans-acting siRNAs”. We are studying the function of genes involved in the biogenesis of trans-acting siRNAs, and are trying to identify the targets and developmental functions of these regulatory siRNAs. Several ta-siRNA targets of already been identified and are being studied to determine their role in the juvenile-to-adult transition.
8
20 Rotation Projects
44 1. Participate in mutant screens for phase change mutations
35 2. Positionally clone newly identified genes
5d 3. Characterize the molecular and developmental phenotype of phase change mutations.
8
1e Lab personnel:
2c Stewart Gillmor, Postdoctoral Fellow
2a Mee Yeon Park, Postdoctoral Fellow
24 Mike Smith, Graduate Student
28 Dennie Tompers, Graduate Student
2d Matthew Willmann, Postdoctoral Fellow
23 Gang Wu, Postdoctoral Fellow
26 7 1d 1f
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