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  • Ewa Bomba-warczak
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Faculty

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Ewa Bomba-Warczak, Ph.D.

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Assistant Professor of Physiology
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Department: Physiology
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1f Graduate Group Affiliations 8 a
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University of Pennsylvania, Department of Physiology
26 626 Clinical Research Building
1b 415 Curie Boulevard
39 Philadelphia, PA 19104
Philadelphia, PA 19014
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Email: ewa.warczak@pennmedicine.upenn.edu
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18 Publications
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13 Education:
21 7 BS 2a (Biological Sciences, w/honors) c
3a University of Illinois at Chicago, 2010.
 21 8 PhD 19 (Neuroscience) c
3c University of Wisconsin – Madison, 2016.
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Links
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Selected Publications

131 Bomba-Warczak E., Savas JN: Long-lived mitochondrial cristae proteins in mouse heart and brain. American Society of Cell Biology 2023 Notes: Poster presentation at Cell Bio 23: ASCB and EMBO meeting, Boston, MA (December 2-6, 2023).

 17e Bomba-Warczak E., Velez K., Zhou L., Guillermier C., Edassery S., Steinhauser M., Savas J., Duncan F.: Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan. bioRxiv 2023.10.18.562852; doi: https://doi.org/10.1101/2023.10.18.562852 (Accepted at eLife) 2023.

 136 Bomba-Warczak E., Savas JN: Long-lived proteins as drivers of neuronal aging. Keystone Conference. March, 24 2023 2023 Notes: Poster Presentation at Keystone Mitochondrial Dysfunction: From Ultra-Rare Diseases to Aging, Breckenridge CO.

 93 Ramirez MA, Ninoyu Y, Miller C, Andrade LR, Edassery S, Bomba-Warczak E., Ortega B, Manor U, Rutherford 73 MA, Friedman RA, Savas JN: Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3. iScience. 2022 4e Jul 20;25(8):104803. doi: 10.1016/j.isci.2022.104803 2022.

 a0 Bomba-Warczak E., Savas JN: Long-lived mitochondrial proteins and why they exist Trends in Cell Biology. 51 2022 Aug;32(8):646-654. doi: 10.1016/j.tcb.2022.02.001. 2022.

 111 Pegg, C.E., Zaichick, S.V., Bomba-Warczak, E., Jovasevic, V., Kim D.H., Kharkwal, H., Wilson, D. W., Walsh, D., Sollars, P.J., Pickard, G.E., Savas, J.S., Smith G. A. : Herpesviruses assimilate kinesin to produce motorized 6f viral particles. Nature 599, 662–666 (2021). doi.org/10.1038/s41586-021-04106-w 2022.

 9a Bomba-Warczak E., Hark TJ., Edassey SL., Savas JN: Long-lived mitochondrial proteins in mouse heart and 67 brain. J Cell Biol (2021) 220 (9): e202005193; doi: 10.1083/jcb.202005193 2021.

 8e Hark TJ, Rao NR, Castillon C, Basta T, Smukowski S, Bao H, Upadhyay A, Bomba-Warczak E., Nomura T, 6a O'Toole ET, Morgan GP, Ali L, Saito T, Guillermier C, Saido TC, Steinhauser ML, Stowell MHB, Chapman ER, 6e Contractor A, Savas JN: Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer's Disease 6e Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals Cell Syst. 2021 Feb 17;12(2):141- 41 158.e9. doi: 10.1016/j.cels.2020.11.007 2021.

 14a Bomba-Warczak E. Hark T., Edassery S. Savas JN: Exceptionally long-lived proteins as pillars of mitochondrial architecture in the aging brains. Society for Neuroscience (SfN) Conference, Chicago IL 2019 Notes: Poster Presentation at Society for Neuroscience. October 19, 2019 14

172 Bomba-Warczak E. Hark T., Edassery S. Savas JN: Exceptionally long-lived proteins as pillars of mitochondrial architecture in the aging brains. Gordon Research Conference. March 23, 2019 2019 Notes: Poster presentation at Gordon Research Conference: Mitochondria in Health and Disease, Ventura CA.

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