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Stephen J. Schuster, M.D.
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Robert and Margarita Louis-Dreyfus Professor in Chronic Lymphocytic Leukemia and Lymphoma Clinical Care and Research
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Attending Physician, Department of Medicine, Division of Hematology-Oncology, Hospital of the University of Pennsylvania
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Director, Lymphoma Translational Research, Abramson Cancer Center of the University of Pennsylvania
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Department: Medicine
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Contact information
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Division of Hematology Oncology
2d Perelman Center for Advanced Medicine
22 12th Floor, South Pavilion
16 Office #12-178
39 3400 Civic Center Blvd
Philadelphia, PA 19104
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2d Perelman Center for Advanced Medicine
22 12th Floor, South Pavilion
16 Office #12-178
39 3400 Civic Center Blvd
Philadelphia, PA 19104
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Office: (215) 349-5330
32 Fax: 215-615-5888
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32 Fax: 215-615-5888
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Publications
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Links
ac Search PubMed for articles
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Education:
21 9 B.S. 17 (Psychology) c
44 Saint Joseph's University, Philadelphia, PA, 1976.
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8b Laboratory Research Technician, Division of Rheumatology, Hahnemann Medical College and Hospital, Philadelphia, PA, 1977.
21 9 M.D. c
44 Jefferson Medical College, Philadelphia, PA, 1981.
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Permanent link21 9 B.S. 17 (Psychology) c
44 Saint Joseph's University, Philadelphia, PA, 1976.
21 5 c
8b Laboratory Research Technician, Division of Rheumatology, Hahnemann Medical College and Hospital, Philadelphia, PA, 1977.
21 9 M.D. c
44 Jefferson Medical College, Philadelphia, PA, 1981.
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3e3 Yegya-Raman, Nikhil. Plastaras, John P. Wright, Christopher M. Chelius, Monica R. Zhang, Siqi. Baron, Jonathan A. Hubbeling, Harper. Sim, Austin J. Robinson, Timothy J. Jain, Michael D. Imber, Brandon S. Fregonese, Beatrice. Yahalom, Joachim. Ladbury, Colton. Dandapani, Savita. Pinnix, Chelsea C. Gunther, Jillian R. Fang, Penny Q. Wu, Susan Y. Dabaja, Bouthaina S. Yang, Joanna C. Chew, Jessica. Braunstein, Steve. Sinha, Sumi. Denlinger, Nathan. Sun, Susan. Terezakis, Stephanie A. Sakthivel, Gukan. Constine, Louis S. Chowdhry, Amit K. Reagan, Patrick M. Burke, Skyler. Tseng, Yolanda D. LaRiviere, Michael J. Maity, Amit. Schuster, Stephen J. Chong, Elise A. Figura, Nicholas B.: Bridging Radiotherapy Prior to Chimeric Antigen Receptor T-Cells for B-Cell Lymphomas: An ILROG Multicenter Study. Blood Adv. 9(13): 3293-3303, Jul 8 2025 Notes: doi: 10.1182/bloodadvances.2025015855.
212 Elghawy, Omar. Wang, Julia. Leung, Olivia J. Swami, Nishwant. Carvajal, Veronica. Yang, Guang. Landsburg, Daniel J. Svoboda, Jakub. Nasta, Sunita D. Chong, Elise A. Schuster, Stephen J. Thomas, Colin J. Carter, Jordan S. Bagg, Adam. Barta, Stefan K.: Clinical Impact of Next-Generation Sequencing of T-Cell Lymphomas: A Single Institution Experience. Clin Lymphoma Myeloma Leuk. 25(7): 505-511, Jul 2025 Notes: doi: 10.1016/j.clml.2025.01.017.
236 Elghawy, Omar. Sussman, Jonathan H. Yang, Austin G. Thomas, Colin J. Carter, Jordan S. Landsburg, Daniel J. Svoboda, Jakub. Kim, Ellen. Rook, Alain H. Chung, Jina. Plastaras, John P. LaRiviere, Michael. Hubbeling, Harper. Chelius, Monica. Nasta, Sunita D. Chong, Elise A. Schuster, Stephen J. Barta, Stefan K.: Pembrolizumab in Relapsed or Refractory Mycosis Fungoides or Sézary Syndrome. JAMA Dermatol. 161(6): 656-658, Jun 1 2025 Notes: doi: 10.1001/jamadermatol.2025.0251.
220 Lϋӧnd, Fabiana. Whalen, Jeanne. Song, Youngchul. Schriefer, Kalyn. Newcombe, Rick. Orlando, Elena J. Choi, Sarah M. Ruella, Marco. Fraietta, Joseph A. Schuster, Stephen J. Brogdon, Jennifer L. Niederst, Matthew J. Treanor, Louise M.: DLBCL cells emerge post CD19 CAR-T with cross-antigen resistance and a gene signature predictive of clinical CAR-T response. Blood Cancer Discov. Jun 27 2025 Notes: doi: 10.1158/2643-3230.BCD-24-0176. Online ahead of print.
280 Awasthi, Rakesh. Grupp, Stephan A. Waldron, Edward. Yanik, Gregory A. Tam, Constantine S. Rives, Susana. McGuirk, Joseph P. Pulsipher, Michael A. Jaeger, Ulrich. Myers, Gary Douglas. Borchmann, Peter. Schuster, Stephen J. Stefanski, Heather E. Bishop, Michael R. Chakraborty, Abhijit. Masood, Aisha. Baruchel, André. Waller, Edmund K.: Evaluation of In vivo CAR Transgene Levels in Tisagenlecleucel-Treated Patients with Relapsed/Refractory B-ALL and DLBCL. Blood Adv. Jun 24 2025 Notes: doi: 10.1182/bloodadvances.2024014995. Online ahead of print.
33a Svoboda, Jakub. Landsburg, Daniel J. Gerson, James. Nasta, Sunita D. Barta, Stefan K. Chong, Elise A. Cook, Michael. Frey, Noelle V. Shea, Joanne. Cervini, Amanda. Marshall, Amy. Four, Megan. Davis, Megan M. Jadlowsky, Julie K. Chew, Anne. Pequignot, Edward. Gonzalez, Vanessa. Noll, Julia Han. Paruzzo, Luca. Rojas-Levine, Juliana. Plesa, Gabriela. Scholler, John. Siegel, Donald L. Levine, Bruce L. Porter, David L. Ghassemi, Saba. Ruella, Marco. Rech, Andrew. Leskowitz, Rachel M. Fraietta, Joseph A. Hwang, Wei-Ting. Hexner, Elizabeth. Schuster, Stephen J. June, Carl H.: Enhanced CAR T-Cell Therapy for Lymphoma after Previous Failure. N Engl J Med. 392(18): 1824-1835, May 8 2025 Notes: doi: 10.1056/NEJMoa2408771.
5bc Jadlowsky, Julie K. Hexner, Elizabeth O. Marshall, Amy. Grupp, Stephan A. Frey, Noelle V. Riley, James L. Veloso, Elizabeth. McConville, Holly. Rogal, Walter. Czuczman, Cory. Hwang, Wei-Ting. Li, Yimei. Leskowitz, Rachel M. Farrelly, Olivia. Karar, Jayashree. Christensen, Shannon. Barber-Rotenberg, Julie. Gaymon, Avery. Aronson, Naomi. Bernstein, Wendy. Melenhorst, Jan Joseph. Roche, Aoife M. Everett, John K. Zolnoski, Sonja A. McFarland, Alexander G. Reddy, Shantan. Petrichenko, Angelina. Cook, Emma J. Lee, Carole. Gonzalez, Vanessa E. Alexander, Kathleen. Kulikovskaya, Irina. Ramírez-Fernández, Ángel. Minehart, Janna C. Ruella, Marco. Gill, Saar I. Schuster, Stephen J. Cohen, Adam D. Garfall, Alfred L. Shah, Payal D. Porter, David L. Maude, Shannon L. Levine, Bruce L. Siegel, Donald L. Chew, Anne. McKenna, Stephen. Lledo, Lester. Davis, Megan M. Plesa, Gabriela. Herbst, Friederike. Stadtmauer, Edward A. Tebas, Pablo. DiNofia, Amanda. Haas, Andrew. Haas, Naomi B. Myers, Regina. O'Rourke, Donald M. Svoboda, Jakub. Tanyi, Janos L. Aplenc, Richard. Jacobson, Jeffrey M. Ko, Andrew H. Cohen, Roger B. June, Carl H. Bushman, Frederic D. Fraietta, Joseph A.: Long-term safety of lentiviral or gammaretroviral gene-modified T cell therapies. Nat Med. 31(4): 1134-1144, Apr 2025 Notes: doi: 10.1038/s41591-024-03478-6.
1f0 Ni, Vincent. Nasta, Sunita D. Barta, Stefan K. Schuster, Stephen J. Chong, Elise A. Svoboda, Jakub. Morrissette, Jennifer J D. Barlev, Ashley. Bagg, Adam. Priore, Salvatore F. Landsburg, Daniel J. : Identification of a clinicopathologic prognostic index for newly diagnosed large B-cell lymphoma patients treated with R-CHOP. Haematologica. 110(4): 1023-1027, Apr 1 2025 Notes: doi: 10.3324/haematol.2024.286560.
244 Maillie, Luke. Nasta, Sunita D. Svoboda, Jakub. Barta, Stefan K. Chong, Elise A. Garfall, Alfred L. Gill, Saar I. Porter, David L. Schuster, Stephen J. Catania, Christopher. Frey, Noelle V. Landsburg, Daniel J.: Prolonged Neurologic Symptoms Following Immune Effector Cell-Associated Neurotoxicity Syndrome in Patients With Large B-cell Lymphoma Treated With Chimeric Antigen Receptor-Modified T Cell Therapy. Transplant Cell Ther. 31(4): 228-235, Apr 2025 Notes: doi: 10.1016/j.jtct.2025.01.884.
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Selected Publications
2ce Furqan, Fateeha. Ahn, Kwang W. Kaur, Manmeet. Patel, Jinalben. Ansell, Stephen. Awan, Farrukh T. Baird, John. Bezerra, Evandro. Farooq, Umar. Fung, Henry. Khurana, Arushi. Lekakis , Lazaros. Lutfi, Forat. McCarty, John. Mukherjee, Akash. Nath, Rajneesh. Romancik, Jason. Schuster, Stephen J. Smith, Melody. Winter, Allison. Turtle, Cameron. Sauter, Craig. Shadman, Mazyar. Herrar, Alex. Hamadani, Mehdi.: Autologous Transplant or CAR-T as Consolidation Options in MYC Rearranged Large B-Cell Lymphoma Patients in Remission After Salvage Treatments. Am J Hematol. 100(7): 1152-1162, Jul 2025 Notes: doi: 10.1002/ajh.27687.3e3 Yegya-Raman, Nikhil. Plastaras, John P. Wright, Christopher M. Chelius, Monica R. Zhang, Siqi. Baron, Jonathan A. Hubbeling, Harper. Sim, Austin J. Robinson, Timothy J. Jain, Michael D. Imber, Brandon S. Fregonese, Beatrice. Yahalom, Joachim. Ladbury, Colton. Dandapani, Savita. Pinnix, Chelsea C. Gunther, Jillian R. Fang, Penny Q. Wu, Susan Y. Dabaja, Bouthaina S. Yang, Joanna C. Chew, Jessica. Braunstein, Steve. Sinha, Sumi. Denlinger, Nathan. Sun, Susan. Terezakis, Stephanie A. Sakthivel, Gukan. Constine, Louis S. Chowdhry, Amit K. Reagan, Patrick M. Burke, Skyler. Tseng, Yolanda D. LaRiviere, Michael J. Maity, Amit. Schuster, Stephen J. Chong, Elise A. Figura, Nicholas B.: Bridging Radiotherapy Prior to Chimeric Antigen Receptor T-Cells for B-Cell Lymphomas: An ILROG Multicenter Study. Blood Adv. 9(13): 3293-3303, Jul 8 2025 Notes: doi: 10.1182/bloodadvances.2025015855.
212 Elghawy, Omar. Wang, Julia. Leung, Olivia J. Swami, Nishwant. Carvajal, Veronica. Yang, Guang. Landsburg, Daniel J. Svoboda, Jakub. Nasta, Sunita D. Chong, Elise A. Schuster, Stephen J. Thomas, Colin J. Carter, Jordan S. Bagg, Adam. Barta, Stefan K.: Clinical Impact of Next-Generation Sequencing of T-Cell Lymphomas: A Single Institution Experience. Clin Lymphoma Myeloma Leuk. 25(7): 505-511, Jul 2025 Notes: doi: 10.1016/j.clml.2025.01.017.
236 Elghawy, Omar. Sussman, Jonathan H. Yang, Austin G. Thomas, Colin J. Carter, Jordan S. Landsburg, Daniel J. Svoboda, Jakub. Kim, Ellen. Rook, Alain H. Chung, Jina. Plastaras, John P. LaRiviere, Michael. Hubbeling, Harper. Chelius, Monica. Nasta, Sunita D. Chong, Elise A. Schuster, Stephen J. Barta, Stefan K.: Pembrolizumab in Relapsed or Refractory Mycosis Fungoides or Sézary Syndrome. JAMA Dermatol. 161(6): 656-658, Jun 1 2025 Notes: doi: 10.1001/jamadermatol.2025.0251.
220 Lϋӧnd, Fabiana. Whalen, Jeanne. Song, Youngchul. Schriefer, Kalyn. Newcombe, Rick. Orlando, Elena J. Choi, Sarah M. Ruella, Marco. Fraietta, Joseph A. Schuster, Stephen J. Brogdon, Jennifer L. Niederst, Matthew J. Treanor, Louise M.: DLBCL cells emerge post CD19 CAR-T with cross-antigen resistance and a gene signature predictive of clinical CAR-T response. Blood Cancer Discov. Jun 27 2025 Notes: doi: 10.1158/2643-3230.BCD-24-0176. Online ahead of print.
280 Awasthi, Rakesh. Grupp, Stephan A. Waldron, Edward. Yanik, Gregory A. Tam, Constantine S. Rives, Susana. McGuirk, Joseph P. Pulsipher, Michael A. Jaeger, Ulrich. Myers, Gary Douglas. Borchmann, Peter. Schuster, Stephen J. Stefanski, Heather E. Bishop, Michael R. Chakraborty, Abhijit. Masood, Aisha. Baruchel, André. Waller, Edmund K.: Evaluation of In vivo CAR Transgene Levels in Tisagenlecleucel-Treated Patients with Relapsed/Refractory B-ALL and DLBCL. Blood Adv. Jun 24 2025 Notes: doi: 10.1182/bloodadvances.2024014995. Online ahead of print.
33a Svoboda, Jakub. Landsburg, Daniel J. Gerson, James. Nasta, Sunita D. Barta, Stefan K. Chong, Elise A. Cook, Michael. Frey, Noelle V. Shea, Joanne. Cervini, Amanda. Marshall, Amy. Four, Megan. Davis, Megan M. Jadlowsky, Julie K. Chew, Anne. Pequignot, Edward. Gonzalez, Vanessa. Noll, Julia Han. Paruzzo, Luca. Rojas-Levine, Juliana. Plesa, Gabriela. Scholler, John. Siegel, Donald L. Levine, Bruce L. Porter, David L. Ghassemi, Saba. Ruella, Marco. Rech, Andrew. Leskowitz, Rachel M. Fraietta, Joseph A. Hwang, Wei-Ting. Hexner, Elizabeth. Schuster, Stephen J. June, Carl H.: Enhanced CAR T-Cell Therapy for Lymphoma after Previous Failure. N Engl J Med. 392(18): 1824-1835, May 8 2025 Notes: doi: 10.1056/NEJMoa2408771.
5bc Jadlowsky, Julie K. Hexner, Elizabeth O. Marshall, Amy. Grupp, Stephan A. Frey, Noelle V. Riley, James L. Veloso, Elizabeth. McConville, Holly. Rogal, Walter. Czuczman, Cory. Hwang, Wei-Ting. Li, Yimei. Leskowitz, Rachel M. Farrelly, Olivia. Karar, Jayashree. Christensen, Shannon. Barber-Rotenberg, Julie. Gaymon, Avery. Aronson, Naomi. Bernstein, Wendy. Melenhorst, Jan Joseph. Roche, Aoife M. Everett, John K. Zolnoski, Sonja A. McFarland, Alexander G. Reddy, Shantan. Petrichenko, Angelina. Cook, Emma J. Lee, Carole. Gonzalez, Vanessa E. Alexander, Kathleen. Kulikovskaya, Irina. Ramírez-Fernández, Ángel. Minehart, Janna C. Ruella, Marco. Gill, Saar I. Schuster, Stephen J. Cohen, Adam D. Garfall, Alfred L. Shah, Payal D. Porter, David L. Maude, Shannon L. Levine, Bruce L. Siegel, Donald L. Chew, Anne. McKenna, Stephen. Lledo, Lester. Davis, Megan M. Plesa, Gabriela. Herbst, Friederike. Stadtmauer, Edward A. Tebas, Pablo. DiNofia, Amanda. Haas, Andrew. Haas, Naomi B. Myers, Regina. O'Rourke, Donald M. Svoboda, Jakub. Tanyi, Janos L. Aplenc, Richard. Jacobson, Jeffrey M. Ko, Andrew H. Cohen, Roger B. June, Carl H. Bushman, Frederic D. Fraietta, Joseph A.: Long-term safety of lentiviral or gammaretroviral gene-modified T cell therapies. Nat Med. 31(4): 1134-1144, Apr 2025 Notes: doi: 10.1038/s41591-024-03478-6.
1f0 Ni, Vincent. Nasta, Sunita D. Barta, Stefan K. Schuster, Stephen J. Chong, Elise A. Svoboda, Jakub. Morrissette, Jennifer J D. Barlev, Ashley. Bagg, Adam. Priore, Salvatore F. Landsburg, Daniel J. : Identification of a clinicopathologic prognostic index for newly diagnosed large B-cell lymphoma patients treated with R-CHOP. Haematologica. 110(4): 1023-1027, Apr 1 2025 Notes: doi: 10.3324/haematol.2024.286560.
244 Maillie, Luke. Nasta, Sunita D. Svoboda, Jakub. Barta, Stefan K. Chong, Elise A. Garfall, Alfred L. Gill, Saar I. Porter, David L. Schuster, Stephen J. Catania, Christopher. Frey, Noelle V. Landsburg, Daniel J.: Prolonged Neurologic Symptoms Following Immune Effector Cell-Associated Neurotoxicity Syndrome in Patients With Large B-cell Lymphoma Treated With Chimeric Antigen Receptor-Modified T Cell Therapy. Transplant Cell Ther. 31(4): 228-235, Apr 2025 Notes: doi: 10.1016/j.jtct.2025.01.884.
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