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Adam D Cohen, MD
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Associate Professor of Medicine (Hematology-Oncology) at the Hospital of the University of Pennsylvania
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Director, Myeloma Immunotherapy, University of Pennsylvania
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Member, Abramson Cancer Center
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Co-Director, Amyloidosis Program, University of Pennsylvania
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Department: Medicine
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Contact information
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Perelman Center for Advanced Medicine
22 12th Floor, South Pavilion
16 Office #12-175
39 3400 Civic Center Blvd
Philadelphia, PA 19104
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22 12th Floor, South Pavilion
16 Office #12-175
39 3400 Civic Center Blvd
Philadelphia, PA 19104
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Office: 215-615-5853
32 Fax: 215-615-5887
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32 Fax: 215-615-5887
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Education:
21 7 BA c
2b Harvard University, 1994.
21 7 MD c
33 University of Pennsylvania, 1999.
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Permanent link21 7 BA c
2b Harvard University, 1994.
21 7 MD c
33 University of Pennsylvania, 1999.
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13 Amyloidosis
16 POEMS syndrome
1f Monoclonal gammopathies
26 Waldenstrom's Macroglobulinemia
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18 Cellular therapy
16 Phase I trials
12 CAR T cells
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Description of Clinical Expertise
21 Multiple Myeloma13 Amyloidosis
16 POEMS syndrome
1f Monoclonal gammopathies
26 Waldenstrom's Macroglobulinemia
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Description of Research Expertise
25 Cancer immunotherapy18 Cellular therapy
16 Phase I trials
12 CAR T cells
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16b Yu KL, Ho M, Paruzzo L, Stella F, Patel H, Hasanali Z, Kapur S, Waxman AJ, Vogl DT, Stadtmauer EA, Fraietta JA, Ruella M, Cohen AD, Garfall AL, Susanibar-Adaniya S: Outcomes of relapse after teclistamab therapy in multiple myeloma. Blood Cancer Journal 2025 Notes: accepted for publication.
1bb Musa H, Mielnik M, Trudel S, Weisel K, Mockus-Daehn T, Ferron-Brady G, Hong Q, Ma Y, Pater S, Suchindran S, Zhou X, Richardson PG, Cohen AD*, Lowther DE*: No evidence of B-cell maturation antigen loss or systemic immune impairment following belantamab mafodotin treatment in multiple myeloma. Haematologica 2025 Notes: 2025 Aug 28. doi: 10.3324/haematol.2025.288203. Online ahead of print 27 *co-senior authors.
274 Jagannath S, Martin TG, Lin Y, Cohen AD, Raje N, Htut M, Deol A, Agha M, Berdeja JG, Lesokhin AM, Liegel JJ, Rossi A, Lieberman-Cribbin A, Usmani SZ, Dhakal B, Parekh S, Li H, Wang F, Montes de Oca R, Plaks V, Sun H, Banerjee A, Schecter JM, Lendvai N, Madduri D, Lengil T, Zhu J, Koneru M, Akram M, Patel N, Costa Filho O, Jakubowiak AJ, Voorhees PM: Long-Term (5-Year) Remission and Survival After Treatment With Ciltacabtagene Autoleucel in CARTITUDE-1 Patients With Relapsed/Refractory Multiple Myeloma. Journal of Clinical Oncology 43: 2766-71, 2025.
150 Ho M, Paruzzo L, Minehart J, Voruganti T, Devi P, Vogl DT, Cohen AD, Garfall AL, Waxman AJ, Kapur S, Stadtmauer EA, Adaniya SS, Longworth S: Non-tuberculous mycobacterial infections following teclistamab in multiple myeloma. Haematologica 110: 1436-42, June 2025.
3b1 98. Jadlowsky JK, Hexner EO, Marshall A, Grupp SA, Frey NV, Riley JL, Veloso E, McConville H, Rogal W, Czuczman C, Hwang WT, Li Y, Leskowitz RM, Farrelly O, Karar J, Christensen S, Barber-Rotenberg J, Gaymon A, Aronson N, Bernstein W, Melenhorst JJ, Roche AM, Everett JK, Zolnoski SA, McFarland AG, Reddy S, Petrichenko A, Cook EJ, Lee C, Gonzalez VE, Alexander K, Kulikovskaya I, Ramírez-Fernández Á, Minehart JC, Ruella M, Gill SI, Schuster SJ, Cohen AD, Garfall AL, Shah PD, Porter DL, Maude SL, Levine BL, Siegel DL, Chew A, McKenna S, Lledo L, Davis MM, Plesa G, Herbst F, Stadtmauer EA, Tebas P, DiNofia A, Haas A, Haas NB, Myers R, O'Rourke DM, Svoboda J, Tanyi JL, Aplenc R, Jacobson JM, Ko AH, Cohen RB, June CH, Bushman FD, Fraietta JA: Long-term safety of lentiviral or gammaretroviral gene-modified T cell therapies. Nature Medicine 31: 1134-1144, Apr 2025.
277 Chen GM, Gering D, Satulovsky J, Datta S, Lai P, Karar J, Gonzalez VE, Alexander K, Chew A, Jadlowsky JK, Moody, Carolan E, Ruella M, Paruzzo L, Amses KR, Stadtmauer EA, Frey NV, Hexner EO, Porter DL, Cohen AD, Gill SI, Garfall AL, Schuster SJ, Mo K, Liang SI, Spasic M, Levine BL, Siegel DL, Ramirez-Fernandez A, Mackall CL, Bushman FD, Good Z, Wherry EJ, June CH, Fraietta JA: Predictive biomarkers of response to chimeric antigen receptor (CAR) T-cell therapy for pan-hematologic cancer. Nature Biomedical Engineering 2025 Notes: accepted for publication.
16a Stalker M, Garfall A, Cohen AD, Vogl DT, Djulbegovic M, Susanibar-Adaniya S, Stadtmauer E, Megherea O, Waxman AJ: Safety and efficacy of teclistamab in patients with relapsed or refractory AL amyloidosis: a retrospective case series. European Journal of Haematology 114: 443-447, Mar 2025.
23f Costa LJ, Banerjee R, Mian H, Weisel KC, Bal S, Derman BA, Htut MM, Nagarajan C, Rodriguez C, Richter J, Frigault MJ, Ye JC, van de Donk NWCJ, Voorhees PM, Puliafito B, Bahlis N, Popat R, Chng WJ, Ho PJ, Kaur G, Kapoor P, Du J, Schjesvold F, Berdeja J, Einsele H, Cohen AD, Mikhael J, Biru Y, Rajkumar SV, Lin Y, Martin TG, Chari A: International Myeloma Working Group Immunotherapy Committee Recommendation on Sequencing Immunotherapy for Treatment of Multiple Myeloma. Leukemia 39: 543-554, Mar 2025.
ed Hasanali ZS, Razzo B, Susanibar-Adaniya SP, Garfall AL, Stadtmauer EA, Cohen AD: CAR T cells in the treatment of Multiple Myeloma. Hematology/Oncology Clinics 2024.
171 Elghawy O, Deshpande S, Sussman J, Garfall A, Cohen A, Kapur S, Susanibar-Adaniya S, Vogl D, Waxman A, Stadtmauer E: Characteristics and outcomes of therapy-related acute leukemia following autologous transplant (auto-HCT) for multiple myeloma. Bone Marrow Transplantation 60(1): 64-68, Jan 2025.
129 Gaballa MR, Puglianini OC, Cohen A, Vogl D, Chung A, Ferreri CJ, Voorhees P, Hansen DK, Patel KK: BCMA-directed CAR T-cell therapy in patients with multiple myeloma and CNS involvement. Blood Advances 9: 1171-1180, Mar 2025.
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Selected Publications
341 Ho M, Paruzzo L, Noll JH, Stella F, Devi P, Ndeupen S, Chen GM, Cohen IJ, Ramirez-Fernandez A, Waxman A, Kapur S, Chen F, Xu R, Huff A, Jarocha D, Patel V, Bochi-Layec AC, Ramasubramanian R, Liu S, Bouvier R, De Souza VB, Petal H, Li Z, Carturan A, Michener P, Hopkins CR, Koucky O, Minehart J, Dimitri A, Nabar NR, Hasanali ZS, Ciccarelli B, Willians E, Bartoszek R, Lavorando M, Suyash M, Gonzalez VE, Porazzi P, Bhoj V, Apostolidis SA, Vogl DT, Porter DL, Scholler J, Diorio C, Roche AM, Everett JK, Bushman FD, Nathanson KL, Stadtmauer EA, Susanibar-Adaniya SP, Garfall AL, Ruella M*, Cohen AD*, Fraietta JA*. : CD4⁺ T-cells mediate ‘CART-associated Immune-Related Adverse Events’ (CirAE) after BCMA CAR T Therapy. Nature Medicine 2025 Notes: accepted for publication 27 *co-senior authors.16b Yu KL, Ho M, Paruzzo L, Stella F, Patel H, Hasanali Z, Kapur S, Waxman AJ, Vogl DT, Stadtmauer EA, Fraietta JA, Ruella M, Cohen AD, Garfall AL, Susanibar-Adaniya S: Outcomes of relapse after teclistamab therapy in multiple myeloma. Blood Cancer Journal 2025 Notes: accepted for publication.
1bb Musa H, Mielnik M, Trudel S, Weisel K, Mockus-Daehn T, Ferron-Brady G, Hong Q, Ma Y, Pater S, Suchindran S, Zhou X, Richardson PG, Cohen AD*, Lowther DE*: No evidence of B-cell maturation antigen loss or systemic immune impairment following belantamab mafodotin treatment in multiple myeloma. Haematologica 2025 Notes: 2025 Aug 28. doi: 10.3324/haematol.2025.288203. Online ahead of print 27 *co-senior authors.
274 Jagannath S, Martin TG, Lin Y, Cohen AD, Raje N, Htut M, Deol A, Agha M, Berdeja JG, Lesokhin AM, Liegel JJ, Rossi A, Lieberman-Cribbin A, Usmani SZ, Dhakal B, Parekh S, Li H, Wang F, Montes de Oca R, Plaks V, Sun H, Banerjee A, Schecter JM, Lendvai N, Madduri D, Lengil T, Zhu J, Koneru M, Akram M, Patel N, Costa Filho O, Jakubowiak AJ, Voorhees PM: Long-Term (5-Year) Remission and Survival After Treatment With Ciltacabtagene Autoleucel in CARTITUDE-1 Patients With Relapsed/Refractory Multiple Myeloma. Journal of Clinical Oncology 43: 2766-71, 2025.
150 Ho M, Paruzzo L, Minehart J, Voruganti T, Devi P, Vogl DT, Cohen AD, Garfall AL, Waxman AJ, Kapur S, Stadtmauer EA, Adaniya SS, Longworth S: Non-tuberculous mycobacterial infections following teclistamab in multiple myeloma. Haematologica 110: 1436-42, June 2025.
3b1 98. Jadlowsky JK, Hexner EO, Marshall A, Grupp SA, Frey NV, Riley JL, Veloso E, McConville H, Rogal W, Czuczman C, Hwang WT, Li Y, Leskowitz RM, Farrelly O, Karar J, Christensen S, Barber-Rotenberg J, Gaymon A, Aronson N, Bernstein W, Melenhorst JJ, Roche AM, Everett JK, Zolnoski SA, McFarland AG, Reddy S, Petrichenko A, Cook EJ, Lee C, Gonzalez VE, Alexander K, Kulikovskaya I, Ramírez-Fernández Á, Minehart JC, Ruella M, Gill SI, Schuster SJ, Cohen AD, Garfall AL, Shah PD, Porter DL, Maude SL, Levine BL, Siegel DL, Chew A, McKenna S, Lledo L, Davis MM, Plesa G, Herbst F, Stadtmauer EA, Tebas P, DiNofia A, Haas A, Haas NB, Myers R, O'Rourke DM, Svoboda J, Tanyi JL, Aplenc R, Jacobson JM, Ko AH, Cohen RB, June CH, Bushman FD, Fraietta JA: Long-term safety of lentiviral or gammaretroviral gene-modified T cell therapies. Nature Medicine 31: 1134-1144, Apr 2025.
277 Chen GM, Gering D, Satulovsky J, Datta S, Lai P, Karar J, Gonzalez VE, Alexander K, Chew A, Jadlowsky JK, Moody, Carolan E, Ruella M, Paruzzo L, Amses KR, Stadtmauer EA, Frey NV, Hexner EO, Porter DL, Cohen AD, Gill SI, Garfall AL, Schuster SJ, Mo K, Liang SI, Spasic M, Levine BL, Siegel DL, Ramirez-Fernandez A, Mackall CL, Bushman FD, Good Z, Wherry EJ, June CH, Fraietta JA: Predictive biomarkers of response to chimeric antigen receptor (CAR) T-cell therapy for pan-hematologic cancer. Nature Biomedical Engineering 2025 Notes: accepted for publication.
16a Stalker M, Garfall A, Cohen AD, Vogl DT, Djulbegovic M, Susanibar-Adaniya S, Stadtmauer E, Megherea O, Waxman AJ: Safety and efficacy of teclistamab in patients with relapsed or refractory AL amyloidosis: a retrospective case series. European Journal of Haematology 114: 443-447, Mar 2025.
23f Costa LJ, Banerjee R, Mian H, Weisel KC, Bal S, Derman BA, Htut MM, Nagarajan C, Rodriguez C, Richter J, Frigault MJ, Ye JC, van de Donk NWCJ, Voorhees PM, Puliafito B, Bahlis N, Popat R, Chng WJ, Ho PJ, Kaur G, Kapoor P, Du J, Schjesvold F, Berdeja J, Einsele H, Cohen AD, Mikhael J, Biru Y, Rajkumar SV, Lin Y, Martin TG, Chari A: International Myeloma Working Group Immunotherapy Committee Recommendation on Sequencing Immunotherapy for Treatment of Multiple Myeloma. Leukemia 39: 543-554, Mar 2025.
ed Hasanali ZS, Razzo B, Susanibar-Adaniya SP, Garfall AL, Stadtmauer EA, Cohen AD: CAR T cells in the treatment of Multiple Myeloma. Hematology/Oncology Clinics 2024.
171 Elghawy O, Deshpande S, Sussman J, Garfall A, Cohen A, Kapur S, Susanibar-Adaniya S, Vogl D, Waxman A, Stadtmauer E: Characteristics and outcomes of therapy-related acute leukemia following autologous transplant (auto-HCT) for multiple myeloma. Bone Marrow Transplantation 60(1): 64-68, Jan 2025.
129 Gaballa MR, Puglianini OC, Cohen A, Vogl D, Chung A, Ferreri CJ, Voorhees P, Hansen DK, Patel KK: BCMA-directed CAR T-cell therapy in patients with multiple myeloma and CNS involvement. Blood Advances 9: 1171-1180, Mar 2025.
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