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Zhi Huang, PhD
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Assistant Professor of Pathology and Laboratory Medicine
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Department: Pathology and Laboratory Medicine
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Graduate Group Affiliations
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Contact information
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3700 Hamilton Walk Room D204
Philadelphia, PA 19104
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Philadelphia, PA 19104
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Office: 3133679531
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Education:
21 7 BS 17 (Automation) c
32 Xi'an Jiaotong University, 2015.
21 7 MS 30 (Electrical and Computer Engineering) c
38 Purdue University, Indianapolis, 2016.
21 8 PhD 30 (Electrical and Computer Engineering) c
3a Purdue University, West Lafayette, 2021.
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Permanent link21 7 BS 17 (Automation) c
32 Xi'an Jiaotong University, 2015.
21 7 MS 30 (Electrical and Computer Engineering) c
38 Purdue University, Indianapolis, 2016.
21 8 PhD 30 (Electrical and Computer Engineering) c
3a Purdue University, West Lafayette, 2021.
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18 Machine Learning
17 Computer Vision
1c Large Language Model
16 Image Analysis
19 Digital Pathology
1d Computational Medicine
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Description of Research Expertise
28 Artificial Intelligence18 Machine Learning
17 Computer Vision
1c Large Language Model
16 Image Analysis
19 Digital Pathology
1d Computational Medicine
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23
3df Melissa E Murray, Colin Smith, Vilas Menon, C Dirk Keene, Ed Lein, Michael Hawrylycz, Adriano Aguzzi, Brett Benedetti, Katja Brose, Kelsey Caetano-Anolles, Maria Inmaculada Cobos Sillero, John F Crary, Philip L De Jager, Arline Faustin, Margaret E Flanagan, Ozgun Gokce, Seth GN Grant, Lea T Grinberg, David A Gutman, Elizabeth MC Hillman, Zhi Huang, David J Irwin, David T Jones, Alifiya Kapasi, Celeste M Karch, Walter T Kukull, Tammaryn Lashley, Edward B Lee, Thomas Lehner, Laura Parkkinen, Maria Pedersen, Dominique Pritchett, Matthew H Rutledge, Julie A Schneider, William W Seeley, Claire E Shepherd, Tara L Spires-Jones, Judith A Steen, Margaret Sutherland, Sanja Vickovic, Bin Zhang, David J Stewart, Michael J Keiser, Jacob W Vogel, Brittany N Dugger, Hemali Phatnani: Accelerating biomedical discoveries in brain health through transformative neuropathology of aging and neurodegeneration. Neuron July 2025.
116 Minghui Chen, Ruinan Jin, Wenlong Deng, Yuanyuan Chen, Zhi Huang, Han Yu, Xiaoxiao Li: Can textual gradient work in federated learning? International Conference on Learning Representations 2025 April 2025.
166 Jacob S Leiby, Alexandro E Trevino, Aaron T Mayer, Zhenqin Wu, Dokyoon Kim, Zhi Huang: Generalized Representation Learning for Multimodal Histology Imaging Data Through Vision-Language Modeling. International Conference on Learning Representations (ICLR) 2025 Workshop LMRL March 2025.
10b Mert Yuksekgonul, Federico Bianchi, Joseph Boen, Sheng Liu, Pan Lu, Zhi Huang, Carlos Guestrin, James Zou: Optimizing generative AI by backpropagating language model feedback. Nature March 2025.
1eb Huang Z, Yang E, Shen J, Gratzinger D, Eyerer F, Liang B, Nirschl J, Bingham D, Dussaq AM, Kunder C, Rojansky R, Gilbert A, Chang-Graham AL, Howitt BE, Liu Y, Ryan EE, Tenney TB, Zhang X, Folkins A, Fox EJ, Montine KS, Montine TJ, Zou J.: A pathologist-AI collaboration framework for enhancing diagnostic accuracies and efficiencies. Nat Biomed Eng no volume(no issue), Jun 2024 Notes: doi: 10.1038/s41551-024-01223-5.
18e Liu R, Wang L, Rizzo S, Garmhausen MR, Pal N, Waliany S, McGough S, Lin YG, Huang Z, Neal J, Copping R, Zou J.: Systematic analysis of off-label and off-guideline cancer therapy usage in a real-world cohort of 165,912 US patients. Cell Rep Med 5(3): 101444, Mar 2024 Notes: doi: 10.1016/j.xcrm.2024.101444. Epub 2024 Feb 29.
167 Weixin Liang, Yaohui Zhang, Zhengxuan Wu, Haley Lepp, Wenlong Ji, Xuandong Zhao, Hancheng Cao, Sheng Liu, Siyu He, Zhi Huang, Diyi Yang, Christopher Potts, Christopher D Manning, James Y Zou: Mapping the increasing use of llms in scientific papers. Conference on Language Modeling 2024.
18e Weixin Liang, Zachary Izzo, Yaohui Zhang, Haley Lepp, Hancheng Cao, Xuandong Zhao, Lingjiao Chen, Haotian Ye, Sheng Liu, Zhi Huang, Daniel A McFarland, James Y Zou: Monitoring ai-modified content at scale: A case study on the impact of chatgpt on ai conference peer reviews. International Conference on Machine Learning 2024.
145 Montine KS, Berson E, Phongpreecha T, Huang Z, Aghaeepour N, Zou JY, MacCoss MJ, Montine TJ.: Understanding the molecular basis of resilience to Alzheimer's disease. Front Neurosci 17(no issue): 1311157, Dec 2023 Notes: doi: 10.3389/fnins.2023.1311157.
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Selected Publications
148 Weixin Liang, Yaohui Zhang, Zhengxuan Wu, Haley Lepp, Wenlong Ji, Xuandong Zhao, Hancheng Cao, Sheng Liu, Siyu He, Zhi Huang, Diyi Yang, Christopher Potts, Christopher D Manning, James Zou: Quantifying large language model usage in scientific papers. Nature Human Behaviour 21 August 2025.3df Melissa E Murray, Colin Smith, Vilas Menon, C Dirk Keene, Ed Lein, Michael Hawrylycz, Adriano Aguzzi, Brett Benedetti, Katja Brose, Kelsey Caetano-Anolles, Maria Inmaculada Cobos Sillero, John F Crary, Philip L De Jager, Arline Faustin, Margaret E Flanagan, Ozgun Gokce, Seth GN Grant, Lea T Grinberg, David A Gutman, Elizabeth MC Hillman, Zhi Huang, David J Irwin, David T Jones, Alifiya Kapasi, Celeste M Karch, Walter T Kukull, Tammaryn Lashley, Edward B Lee, Thomas Lehner, Laura Parkkinen, Maria Pedersen, Dominique Pritchett, Matthew H Rutledge, Julie A Schneider, William W Seeley, Claire E Shepherd, Tara L Spires-Jones, Judith A Steen, Margaret Sutherland, Sanja Vickovic, Bin Zhang, David J Stewart, Michael J Keiser, Jacob W Vogel, Brittany N Dugger, Hemali Phatnani: Accelerating biomedical discoveries in brain health through transformative neuropathology of aging and neurodegeneration. Neuron July 2025.
116 Minghui Chen, Ruinan Jin, Wenlong Deng, Yuanyuan Chen, Zhi Huang, Han Yu, Xiaoxiao Li: Can textual gradient work in federated learning? International Conference on Learning Representations 2025 April 2025.
166 Jacob S Leiby, Alexandro E Trevino, Aaron T Mayer, Zhenqin Wu, Dokyoon Kim, Zhi Huang: Generalized Representation Learning for Multimodal Histology Imaging Data Through Vision-Language Modeling. International Conference on Learning Representations (ICLR) 2025 Workshop LMRL March 2025.
10b Mert Yuksekgonul, Federico Bianchi, Joseph Boen, Sheng Liu, Pan Lu, Zhi Huang, Carlos Guestrin, James Zou: Optimizing generative AI by backpropagating language model feedback. Nature March 2025.
1eb Huang Z, Yang E, Shen J, Gratzinger D, Eyerer F, Liang B, Nirschl J, Bingham D, Dussaq AM, Kunder C, Rojansky R, Gilbert A, Chang-Graham AL, Howitt BE, Liu Y, Ryan EE, Tenney TB, Zhang X, Folkins A, Fox EJ, Montine KS, Montine TJ, Zou J.: A pathologist-AI collaboration framework for enhancing diagnostic accuracies and efficiencies. Nat Biomed Eng no volume(no issue), Jun 2024 Notes: doi: 10.1038/s41551-024-01223-5.
18e Liu R, Wang L, Rizzo S, Garmhausen MR, Pal N, Waliany S, McGough S, Lin YG, Huang Z, Neal J, Copping R, Zou J.: Systematic analysis of off-label and off-guideline cancer therapy usage in a real-world cohort of 165,912 US patients. Cell Rep Med 5(3): 101444, Mar 2024 Notes: doi: 10.1016/j.xcrm.2024.101444. Epub 2024 Feb 29.
167 Weixin Liang, Yaohui Zhang, Zhengxuan Wu, Haley Lepp, Wenlong Ji, Xuandong Zhao, Hancheng Cao, Sheng Liu, Siyu He, Zhi Huang, Diyi Yang, Christopher Potts, Christopher D Manning, James Y Zou: Mapping the increasing use of llms in scientific papers. Conference on Language Modeling 2024.
18e Weixin Liang, Zachary Izzo, Yaohui Zhang, Haley Lepp, Hancheng Cao, Xuandong Zhao, Lingjiao Chen, Haotian Ye, Sheng Liu, Zhi Huang, Daniel A McFarland, James Y Zou: Monitoring ai-modified content at scale: A case study on the impact of chatgpt on ai conference peer reviews. International Conference on Machine Learning 2024.
145 Montine KS, Berson E, Phongpreecha T, Huang Z, Aghaeepour N, Zou JY, MacCoss MJ, Montine TJ.: Understanding the molecular basis of resilience to Alzheimer's disease. Front Neurosci 17(no issue): 1311157, Dec 2023 Notes: doi: 10.3389/fnins.2023.1311157.
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