Rachel C Jankowitz, MD
Associate Professor of Clinical Medicine (Hematology-Oncology)
Director, Rena Rowan Breast Center , University of Pennsylvania
Section Chief, Breast Medical Oncology, Penn Medicine Abramson Cancer Center
Department: Medicine
Contact information
Perelman Center for Advanced Medicine
South Pavilion, 10th Floor, Room 10-156
Philadelphia, PA 19104
South Pavilion, 10th Floor, Room 10-156
Philadelphia, PA 19104
Office: 215-615-5858
Fax: 215-615-5858
Fax: 215-615-5858
Education:
BA (Biology, Magna Cum Laude)
Fairfield University , 1999.
MD (Medicine)
Temple University School of Medicine , 2003.
Permanent linkBA (Biology, Magna Cum Laude)
Fairfield University , 1999.
MD (Medicine)
Temple University School of Medicine , 2003.
Description of Clinical Expertise
Breast Cancer, invasive lobular carcinoma, breast cancer clinical trials.Description of Research Expertise
Breast Cancer, invasive lobular carcinoma, breast cancer clinical trials.Selected Publications
Gradishar WJ, Moran MS, Abraham J, Abramson V, Aft R, Agnese D, Allison KH, Anderson B, Bailey J, Burstein HJ, Chen N, Chew H, Dang C, Elias AD, Giordano SH, Goetz MP, Jankowitz RC, Javid SH, Krishnamurthy J, Leitch AM, Lyons J, McCloskey S, McShane M, Mortimer J, Patel SA, Rosenberger LH, Rugo HS, Santa-Maria CA, Schneider BP, Smith ML, Soliman H, Stringer-Reasor EM, Telli ML, Wei M, Wisinski KB, Yellala A, Yeung KT, Young JS, Schonfeld R, Kumar R.: NCCN Guidelines® Insights: Breast Cancer, Version 5.2025 J Natl Compr Canc Netw 23(11): 426-436, Nov 2025 Notes: doi: 10.6004/jnccn.2025.0053. PMID: 41213254.Kai Ding, Lyuqin Chen, Kevin M Levine, Matthew J Sikora, Nilgun Tasdemir, David Dabbs, Rachel Jankowitz, Rachel Hazan, Osama Shah, Jenny Atkinson, Adrian V Lee, Steffi Oesterreich: FGFR4 in endocrine resistance: overexpression and estrogen regulation without direct causative role. Breast Cancer Res Treat 211(2): 501-515, Jun 2025.
Peter Schmid 1, Javier Cortes 1, Rebecca Dent 1, Heather McArthur 1, Lajos Pusztai 1, Sherko Kümmel 1, Carsten Denkert 1, Yeon Hee Park 1, Rina Hui 1, Nadia Harbeck 1, Masato Takahashi 1, Seock-Ah Im 1, Michael Untch 1, Peter A Fasching 1, Marie-Ange Mouret-Reynier 1, Theodoros Foukakis 1, Marta Ferreira 1, Fatima Cardoso 1, Xuan Zhou 1, Vassiliki Karantza 1, Konstantinos Tryfonidis 1, Gursel Aktan 1, Joyce O'Shaughnessy 1; KEYNOTE-522 InvestigatorsKEYNOTE-522 Investigators: Yoland Antill, Phuong Dinh, Rina Hui, Po-Ling Inglis, Alexander M Menzies, Sally Baron-Hay, Nick Murray, Jacqui Thomson, Daphne Tsoi, Carlos Henrique E Barrios, João Daniel Cardoso Guedes, Gustavo Colagiovanni Girotto, Ademar Dantas da Cunha Jr, Rita de Cassia Costamilan, Fabio de Figueiredo Chaves, Ruffo de Freitas Jr, Rudinei Diogo Marques Linck, Jose Luiz Pedrini, Nils Gunnar Skare, Jean-Francois Boileau, David Cescon, Saima Hassan, Andre Robidoux, Michel Pavic, Brigitte Poirier, Louise Provencher, Xinni Song, Marc Webster, Sunil Verma, Ana Cristina Avendano Rojas, Ricardo Bruges, Diego Mauricio Gonzalez, Maria Elvira Montoya Restrepo, Manuel Enrique Gonzalez Fernandez, Paola Andrea Pinilla, Jesus Oswaldo Sanchez Castillo, Luis Leonardo Rojas, Gustova Adolfo Rojas-Uribe, Hugues Bourgeois, Stephanie Chieze, Dorothee Chocteau-Bouju, Florence Dalenc, Catherine Delbaldo, Nadine Dohollou, Sylvie Giacchetti, Christelle Levy, Laura Mansi, Loic Chaigneau, Marie-Ange Mouret-Reynier, Marie-Paule Sablin, Delphine Loirat, Mustafa Deryal, Peter A Fasching, Eva-Maria Grischke, Tobias Engler, Andreas Hartkopf, Nadia Harbeck, Christian Martin Kurbacher, Volkmar Mueller, Isabell Witzel, Mattea Reinisch, Christoph Thomssen, Michael Untch, Conleth Murphy, Janice Walshe, Rotem Merose, Adi Rasco, Daniella Katz, Einav Nili-Gal-Yam, Bella Kaufman, Shani Paluch-Shimon, Tamar Peretz-Yablonski, Salomon Stemmer, Margarita Tokar, David Geffen, Ido Wolf, Ella Evron, Larisa Ryvo, Editta Baldini, Nicola Battelli, Giovanni Beneditti, Marco Colleoni, Michelino De Laurentiis, Ugo di Giorgi, Andrea Rocco, Rebecca Pedersini, Shoko Hayama, Naohito Yamamoto, Mitsuya Itoh, Shoichiro Ohtani, Yoshifumi Komoike, Haruru Kotani, Hiroji Iwata, Masaya Hattori, Hideki Maeda, Masato Takahashi, Yasuo Miyoshi, Hirofumi Mukai, Shigenori Nagai, Kenichi Inoue, Naoki Niikura, Yutaka Tokuda, Akihiko Osaki, Toshiaki Saeki, Yasuaki Sagara, Toshimi Takano, Shinji Ohno, Yukiko Tadokoro, Junichiro Watanabe, Yuko Tanabe, Koichiro Tsugawa, Yutaka Yamamoto, Hiroyuki Yasojima, Norikazu Masuda, Kan Yonemori, Chikako Shimizu, Kenji Tamura, Atsushi Yoshida, Naoki Hayashi, Barbara Bauer-Kosinska, Ewa Chmielowska, Agata Chrzanowska-Kapica, Iwona Danielewicz, Krzysztof Lesniewski Kmak, Anna Patrycja Drosik Kwasniewska, Aleksandra Grela-Wojewoda, Aleksandra Lacko, Rafal Tarnawski, Bogdan Zurawski, Fatima Cardoso, Leonor Castro Abreu Ribeiro, Maria Rita Dionísio, Rita Teixeira Sousa, Marta Ferreira, Jin-Hee Ahn, Seock-Ah Im, Min Hwan Kim, Gun Min Kim, Yeon Hee Park, Yana S Chapko, Lyudmila N Lebedeva, Marina N Nechaeva, Natalia Vladmirovna Fadeeva, Inna Ganshina, Mikhail Romanovich Lichinitser, Petr Vladimirovich Krivorotko, Oleg Nikolaevich Lipatov, Guzel Zinnurovna Mukhametshina, Marina V Shomova, Rebecca Dent, Joan Albanell Mestres, Begona Bermejo de Las Heras, Juan de la Haba Rodriguez, Maria Gión Cortes, Esther Holgado Martin, Lucia Gonzalez Cortijo, Rafael Lopez Lopez, Javier Salvador Bofill, Jesus Soberino Garcia, Jose Manuel Perez Garcia, Rafael Villanueba Vazquez, Idoia Morilla Ruiz, Esther Zamora Adelantado, Eva Munoz Couselo, Ahmed Albu-Kareem, Anna-Lotta Hallbeck, Anne Andersson, Theodoros Foukakis, Henrik Lindman, Yuan-Ching Chang, Shin-Cheh Chen, Chi-Feng Chung, Mei- Ching Liu, Chiun-Sheng Huang, Kuo-Ting Lee, Ling-Ming Tseng, Huseyin Abali, Sercan Aksoy, Cagatay Arslan, Gul Basaran, Erhan Gokmen, Ruchan F Uslu, Cengiz Karacin, Berna Oksuzoglu, Serkan Keskin, Nil Molinas Mandel, Evren Ozdemir, Mustafa Ozdogan, Mustafa Ozguroglu, Ozgur Ozyilkan, Sernaz Topaloglu, Irfan Cicin, Bahiddin Yilmaz, Idris Yucel, Steve Chan, Janine Elizabeth Graham, Catherine Harper-Wynne, Fiona Kyle, M B Mukesh, Peter Schmid, Duncan Wheatley, Haythem Ali, Jay C Andersen, Chiara Battelli, Adam Brufsky, Leisha Ann Emens, Rachel Jankowitz, Michelina Cairo, Frankie Ann Holmes, Jenny Chang, Arvind Chaudhry, Aaron Chevinsky, William MacLaughlin, Elizabeth K Chung, Thomas D Weyburn, Michael A Danso, Jennifer Robinson Diamond, Patrick Dillon, Mary Anne Fenton, Mary Lopresti, Michael S Gordon, Jasgit Sachdev, Barbara B Haley, Ronald P Harris, Allyson Harroff, Sharon T Wilks, William J Irvin, Michael Zachary Koontz, Laura Stampleman, Ebenezer Kio, Daniel G Bruetman, Timothy G Larson, Michaela Tsai, Jose Leone, Sneha Phadke, Siva Mannem, Sri Obulareddy, Vicky E Jones, Omkar Marathe, Eddie Thara, Apurva Mehta, Jamal Misleh, Michael J Guarino, Monica M Mita, Reva Basho, Heather McArthur, Rita Nanda, Ira A Oliff, Joyce A OShaughnessy, David Page, Debra A Patt, Lajos Pusztai, Donald A Richards, Irina Rybalova, Poornima Saha, Jennifer Specht, Alexander I Spira, Neelima Denduluri, Christopher T F Stokoe, Rachel Swart, Deborah Lynn Toppmeyer, Frances Valdes, Gregory Vidal, Patrick Ward, Ying Zhuo, Javier Cortes, Carsten Denkert, Sherko Kuemmel: Overall Survival with Pembrolizumab in Early-Stage Triple-Negative Breast Cancer. N Engl J Med 391(21): 1981-1991, Nov 2024.
Gradishar WJ, Moran MS, Abraham J, Abramson V, Aft R, Agnese D, Allison KH, Anderson B, Bailey J, Burstein HJ, Chen N, Chew H, Dang C, Elias AD, Giordano SH, Goetz MP, Jankowitz RC, Javid SH, Krishnamurthy J, Leitch AM, Lyons J, McCloskey S, McShane M, Mortimer J, Patel SA, Rosenberger LH, Rugo HS, Santa-Maria C, Schneider BP, Smith ML, Soliman H, Stringer-Reasor EM, Telli ML, Wei M, Wisinski KB, Yeung KT, Young JS, Schonfeld R, Kumar R.: Breast Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw Jul 2024.
Oesterreich S, Pate L, Lee AV, Chen F, Jankowitz RC, Mukhtar R, Metzger O, Sikora MJ, Li CI, Sotiriou C, Shah OS, Koorman T, Ulaner G, Reis-Filho JS, Davidson NM, Van Baelen K, Hutcheson L, Freeney S, Migyanka F, Turner C, Derksen P, Bear T, Desmedt C.: International survey on invasive lobular breast cancer identifies priority research questions. NPJ Breast Cancer Jul 2024.
Tarantino P, Tayob N, Villacampa G, Dang C, Yardley DA, Isakoff SJ, Valero V, Faggen M, Mulvey T, Bose R, Weckstein D, Wolff AC, Reeder-Hayes K, Rugo HS, Ramaswamy B, Zuckerman D, Hart L, Gadi VK, Constantine M, Cheng K, Garrett AM, Marcom PK, Albain K, DeFusco P, Tung N, Ardman B, Nanda R, Jankowitz RC, Rimawi M, Abramson V, Pohlmann PR, Van Poznak C, Forero-Torres A, Liu MC, Ruddy KJ, Waks AG, DeMeo M, Burstein HJ, Partridge AH, Dell'Orto P, Russo L, Krause E, Newhouse DJ, Kurt BB, Mittendorf EA, Schneider B, Prat A, Winer EP, Krop IE, Tolaney SM; Consortium of the TBCRC Translational Investigators; TBCRC Translational Investigators.: Adjuvant Trastuzumab Emtansine Versus Paclitaxel Plus Trastuzumab for Stage I Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: 5-Year Results and Correlative Analyses From ATEMPT. J. Clin Oncol Jun 2024.
Gradishar WJ, Moran MS, Abraham J, Abramson V, Aft R, Agnese D, Allison KH, Anderson B, Bailey J, Burstein HJ, Chen N, Chew H, Dang C, Elias AD, Giordano SH, Goetz MP, Jankowitz RC, Javid SH, Krishnamurthy J, Leitch AM, Lyons J, McCloskey S, McShane M, Mortimer J, Patel SA, Rosenberger LH, Rugo HS, Santa-Maria C, Schneider BP, Smith ML, Soliman H, Stringer-Reasor EM, Telli ML, Wei M, Wisinski KB, Yeung KT, Young JS, Schonfeld R, Kumar R.: Breast Cancer, Version 3.2022, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 22(5): 331-357, Jun 2024 Notes: doi: 10.6004/jnccn.2024.0035.
Jacobs SA, Wang Y, Abraham J, Feng H, Montero AJ, Lipchik C, Finnigan M, Jankowitz RC, Salkeni MA, Maley SK, Puhalla SL, Piette F, Quinn K, Chang K, Nagy RJ, Allegra CJ, Vehec K, Wolmark N, Lucas PC, Srinivasan A, Pogue-Geile KL.: NSABP FB-10: a phase Ib/II trial evaluating ado-trastuzumab emtansine (T-DM1) with neratinib in women with metastatic HER2-positive breast cancer. Breast Cancer Res Apr 2024.
Ding K, Chen L, Levine K, Sikora M, Tasdemir N, Dabbs D, Jankowitz R, Hazan R, Shah OS, Atkinson JM, Lee AV, Oesterreich S.: Estrogen regulation and functional role of FGFR4 in estrogen receptor positive breast cancer. bioRxiv [Preprint] Mar 2024.
Sanft TB, Wong J, O'Neal B, Siuliukina N, Jankowitz RC, Pegram MD, Fox JR, Zhang Y, Treuner K, O'Shaughnessy JA. : Impact of the Breast Cancer Index for Extended Endocrine Decision-Making: First Results of the Prospective BCI Registry Study. J Natl Compr Canc Netw. 22(2): 99-107, Mar 2024.