Perelman School of Medicine at the University of Pennsylvania

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Latest News

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  • Mimicking natural connections could improve rotator cuff repair August 24, 2026 Many rotator cuff repairs fail due to a variety of factors that could be solved by a new fix that imitates the body’s natural environment.
  • A lifeguard's warning sign: how Kevin Comerford's emergency saved three lives August 19, 2026 When a Jersey Shore lifeguard experienced sudden pain, he never expected it would lead to life saving surgery for him and two of his family members.
  • Penn Medicine experts explain the science behind later school start times August 18, 2026 Penn Medicine experts explain how later school start times may support teen sleep, learning, safety, and mental health.
  • Penn researchers join ARPA-H initiative to develop next-gen fetal monitoring device August 05, 2026 Clinicians may soon have a clearer picture of how babies are tolerating labor through a new federally funded effort to develop a wearable monitor.
  • Immune-inspired public health strategy improves detection of disease-carrying insects August 04, 2026 A decentralized approach modeled on the immune system detected more disease-carrying insects than conventional surveillance in Peru.

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Featured Publications

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  • Integrative spatial profiling of 3D genome organization and gene expression in tissue.
    Guo P, Cui Y, He J, Waldman AJ, Zhu J, Chen Y, Huang Z, ... Cell. 2026 Aug 25
  • TDP-43-Associated Neurodegenerative Disease Conceptualization and Integrated Staging: A Review.
    Benatar M, Barmada S, Jicha GA, Lagier-Tourenne C, Gregory J, Al-Chalabi A, Boeve BF, ... JAMA neurology. 2026 Aug 24
  • Single-allele chromatin tracing reveals cytokine-dependent super-enhancer repositioning in CD4(+) T cells.
    Jay A, Zhou Y, Yoon S, Abeje BN, Chandra A, Michieletto MF, Wald J, ... Immunity. 2026 Aug 24
  • Adaptive model-guided protein evolution with sparse data optimizes compact eukaryotic genome editors.
    Wan S, Gold J, Vure P, Mogilevsky CS, Talikoti A, Chen T, Gupta A, ... Nature biotechnology. 2026 Aug 24
  • Neurodegeneration as a dysregulation of neuroimmune crosstalk.
    Bennett FC, Hong S, Jiang N, Marazzi I Cell. 2026 Aug 20;189(17):5156-5173

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Perelman School of Medicine
University of Pennsylvania
3400 Civic Center Boulevard
Building 421, Philadelphia, PA 19104

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