Mutations in the human CSF1R gene impact microglia's maintenance of brain white matter integrity

Du S, Zhou Y, Li D, Lier J, Cella M, Tada M, Hamasaki H, Wu J, Cai Z, Orthmann-Murphy JL, Kakita A, Kipnis J, Bergner CG, Colonna M. Nat Immunol. 2025 Jul;26(7):1198-1211. doi: 10.1038/s41590-025-02195-7. Epub 2025 Jun 26. PMID: 40571738